DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37C2 and RGD1559459

DIOPT Version :9

Sequence 1:	NP_001260516.1	Gene:	Ugt37C2 / 53513	FlyBaseID:	FBgn0040262	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	XP_003751392.1	Gene:	RGD1559459 / 501907	RGDID:	1559459	Length:	530	Species:	Rattus norvegicus

Alignment Length:	520	Identity:	149/520 - (28%)
Similarity:	250/520 - (48%)	Gaps:	52/520 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SHLIIHMSVAKALVKAGHNVTVVSMLKPKVTHK---------------------DIHLIVVPMKE 76
            ||.:....:...|||.||.|.|   |||.|:..                     |:.:|.:.
  Rat    34 SHWLNLKIILSELVKKGHEVVV---LKPSVSFSYEVDKTSAIEFESFPSSYSIADVEVIFMD--- 92

  Fly    77 EQERIMEDQMTEMAGQKNSLVSTMYRLLTSMDVMINAQAELLSDPRFQRIYETK-----FDLMIL 136
                .:.:.:.|:  .|.|.......|....:...:....|..|..|.:...||     ||:::.
  Rat    93 ----CVNESIYEL--PKQSFWGYFLMLQKLFERTSDYSERLCRDAAFNKELMTKLQNSGFDVILA 151

  Fly   137 GYFINDFQLGVAHKLKVPVIINWMSAPVPAIDKYTGN-PSELSYVPLMGTVATQPMGFLKRTENA 200
            ..|.....| :|..||:|::.:....|....:||:|. |...||||:..:..:..|.|::|.::.
  Rat   152 DPFTPCGDL-LAEILKIPLVYSLRFFPGSTYEKYSGGLPMPPSYVPIAMSELSDRMTFVERVKHM 215

  Fly   201 LKSLLFEFIFVVFD-YKLTRIYNDVFPEQDMPTLKELRKNISMAFVGSHLISEGPIRPLVPALIE 264
            :..|.|:|.|.||| .|...:|.:|....  .||.|......:..:.::...|.| .|::|....
  Rat   216 IYVLCFDFWFQVFDEKKWNELYTEVLGRP--TTLSETMAKADIWLIRTYWDLEFP-HPVLPNFDF 277

  Fly   265 IGGIQVKDKPDPLPKDIDQFI-SNAKQGAVFLSLGSNVKSSTVRPEIVQIIFKVLSELKENVIWK 328
            :||:..: ...||||:|:.|: |:.:.|.|..||||.|.|.|  .|...:|...|:::.:.|:|:
  Rat   278 VGGLHCR-PAKPLPKEIEDFVQSSGEHGVVVFSLGSMVGSLT--EERANVIAAGLAQIPQKVLWR 339

  Fly   329 WEDLENTPGNSSNILYKNWLPQDDILAHPNTKLFITHAGKGGITEAQYHGVPMVALPIFGDQPGN 393
            :|..:.....|:..||| |:||:|:|.||.|:.||||.|..||.||.|||:|:|.:|:||||..|
  Rat   340 FEGKKPETLGSNTRLYK-WIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPVVGIPLFGDQKDN 403

  Fly   394 AALMEKSGYGLALDLLSITEDSLRDALKEVLENQKYKQAIGQFSTLYRDRPMTAKQSVVFWTEYI 458
            ...::..|..:.||.|:::...|..||:.|..:..||:...:.|.::.|:|:......|||.|::
  Rat   404 IVHLKTKGAAVRLDFLTMSSTDLLTALRTVTNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFV 468

  Fly   459 LRHQGAPNLQSPSVHMNFIQLNNLDIYALIVTILVLFVLLTRLVAKIVWNKFGGKAKISQTKKKQ 523
            :||:||.:|:.....::::|.::||:...::..:|..:.:.:........||   .|..:.|||:
  Rat   469 MRHKGAKHLRVAGHDLSWVQYHSLDVIGFLLACVVTVMFILKKCCLFCCQKF---TKAGRKKKKE 530

Fly 524 523
Rat 531 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	138/462 (30%)
Ugt37C2	NP_001260516.1	UDPGT	33..515	CDD:278624	145/510 (28%)
RGD1559459	XP_003751392.1	UDPGT	24..527	CDD:278624	146/515 (28%)
RGD1559459	XP_003751392.1	egt	<270..508	CDD:223071	84/241 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344117
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.740