DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37C2 and ugt-39

DIOPT Version :9

Sequence 1:	NP_001260516.1	Gene:	Ugt37C2 / 53513	FlyBaseID:	FBgn0040262	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_504816.2	Gene:	ugt-39 / 3564933	WormBaseID:	WBGene00017329	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	547	Identity:	137/547 - (25%)
Similarity:	238/547 - (43%)	Gaps:	65/547 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FVFLLLLGVVASTQGANILGLFSSHSPSHLIIHMSVAKALVKAGHNV-----TVVSMLK----PK 61
            |:..|..|.|:|   .|.|......:.||.....::|.:|..|||||     |:|...:    .|
Worm     5 FILFLFFGNVSS---FNFLVFCPLFAHSHSKFFATIADSLTDAGHNVTFFTPTIVEKYRNVSYTK 66

  Fly    62 VTHKDIHLIVVPMKEEQERIMEDQMTEMAGQ------KNSLVSTMYRLLTSMDVMINAQAELLSD 120
            .|...:|:  .|.|:.:|  ..:||:  .|.      ::|..:.:..::.....|.|.|..::.|
Worm    67 STKDVVHM--KPSKKLKE--YGEQMS--TGDFVRYWTEDSTATEIIPVVRIFQKMYNEQGTVMKD 125

  Fly   121 --PRFQRIYETKFDLMIL-GYFINDFQLGVAHKLKVPVIINWMSAPVPAIDKYTGNPSELSYVPL 182
              .....:.:.|||::|. .|..:.:.|  ...|::|..|     |..::...|....|:. .|:
Worm   126 NVGILNELKKRKFDVIIFEAYIYSAYPL--MDYLEIPTFI-----PSVSVAHDTSLAIEIG-EPV 182

  Fly   183 MGTVAT---QPMG-FLKRTENALKSLLFEFIFVVFDYKLTRIYNDVFPEQDMPTLKELRKNISMA 243
            |.:|.:   .|.| .|..||.|..:.:..:...:..|...|.:.   |..:...::.:....|..
Worm   183 MPSVVSDCLSPFGDKLSITERAFNAFMVPYFDFMIGYPTHRSFK---PPYNPIDIRSIVPEASFV 244

  Fly   244 FVGSHLISEGPIRPLVPALIEIGGIQVKDKPDPLPKDIDQF---ISNAKQGAVFLSLGSNVKSST 305
            |:.|:...:.| ||.:...|:||||.| |..:...:.:|:.   |...::..:.:|.||.:.|..
Worm   245 FLNSNPFVDFP-RPTLTKTIQIGGISV-DSNELRSQKLDETWSEILKLREKTMLVSFGSMLYSKD 307

  Fly   306 VRPEIVQIIFKVLSELKENV--IWKWEDLENTPGNSS--------NILYKNWLPQDDILAHPNTK 360
            : |...:|..|...|..:||  |||:||      :||        ||.:..|:||..:||.....
Worm   308 M-PFKNKIALKNAMEKFKNVTFIWKYED------DSSDEFAKGIENIHFAKWVPQTALLADSRLS 365

  Fly   361 LFITHAGKGGITEAQYHGVPMVALPIFGDQPGNAALMEKSGYGLALDLLSITE-DSLRDALKEVL 424
            .|:||||.|.|.|..|.|.|.:..|...||..||.::.:....:.|....:.: :.:.:|.:.:|
Worm   366 AFLTHAGLGSINELSYLGKPAILCPQLFDQMRNAKMLVRHNGSIELSKYDLGDSEKIVNAFQAIL 430

  Fly   425 ENQKYKQAIGQFSTLYRDRPMTAKQSVVFWTEYILRHQGAPNLQSPSVHMNFIQLNNLDIYALIV 489
            .:..|.:...:.:....::|:..|:.:|...|:..|....|:|...|..|.||:...:|:.|:.:
Worm   431 FDSSYAKNALKLAEQLENQPIKPKEMMVKHAEFAARFGRLPSLDPYSRKMTFIEYFLIDVAAISM 495

  Fly   490 TILVLFVLLTRLVAKIVWNKFGGKAKI 516
            .:|:..|.:...:.||:.||...|.||
Worm   496 VVLIAVVFVITKMFKILCNKTSVKGKI 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	121/496 (24%)
Ugt37C2	NP_001260516.1	UDPGT	33..515	CDD:278624	128/517 (25%)
ugt-39	NP_504816.2	Glycosyltransferase_GTB_type	12..503	CDD:299143	127/519 (24%)
ugt-39	NP_504816.2	UDPGT	29..521	CDD:278624	128/517 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810