Protein Alignment Ugt37C2 and Ugt1a2

DIOPT Version :9

• Sequence 1: NP_001260516.1
• Gene: Ugt37C2 / 53513
• FlyBaseID: FBgn0040262
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_038729.1
• Gene: Ugt1a2 / 22236
• MGIID: 3576049
• Length: 533
• Species: Mus musculus
• Alignment Length: 548
• Identity: 164/548 - (29%)
• Similarity: 277/548 - (50%)
• Gaps: 65/548 - (11%)

  Fly     9 LLLLGVVASTQGANILGLFSSHSPSHLIIHMSVAKALVKAGHNVTVVSMLKPKVTHKDIHL---- 69
            ||||..:...:||.:|.|  ....|..:....|.:.|...||...|   |..:||   :|:
Mouse    16 LLLLCALPWAEGAKVLVL--PMEGSQWLSMRDVVRELHARGHQTVV---LASEVT---VHIKGED 72

  Fly    70 ------IVVP-MKEE-QERIMEDQMTEMAGQKNSLVSTMYRLLTSM----DVMINAQAELLSDPR 122
                  ...| .||| |:.|:.|  .|...:....|...:....|:    |:..|:...||.:..
Mouse    73 FFTLKTYAFPYTKEEYQQEILSD--IEKTFKTQHFVKAFFETTASIRNFFDLYSNSCIALLHNKM 135

  Fly   123 -FQRIYETKFDLMILGYFINDFQLG--VAHKLKVPVIINWMSAPVPAIDKYTGNPSELSYVPLMG 184
             .|::..:.||:::....   |..|  :|..|::|.:....|.......:.|..|:..||:|.:.
Mouse   136 LIQQLNSSFFDVILTDPI---FPCGAVLAKYLQIPAVFILRSLSCGIEYEATQCPNPSSYIPNLL 197

  Fly   185 TVATQPMGFLKRTENALKSLLFEFIFVVFDYKLTRIYNDVFPEQDMPTLKELRKNISMAFVGSH- 248
            |..:..|.||:|.:|.|..|:.::|        .|:  .:.|.:.:.: :.|::.:|:..|.||
Mouse   198 TRLSDHMDFLQRVQNMLYYLVLKYI--------CRL--SITPYESLAS-ELLQREVSLVEVLSHA 251

  Fly   249 --------LISEGPIRPLVPALIEIGGIQVKDKPDPLPKDIDQFI-SNAKQGAVFLSLGSNVKSS 304
                    .:.:.| ||::|.::.||||....| .||.::.:.:: ::.:.|.|..||||.|  |
Mouse   252 SVWLFRGDFVLDYP-RPIMPNMVFIGGINCVTK-KPLSQEFEAYVNASGEHGIVVFSLGSMV--S 312

  Fly   305 TVRPEIVQIIFKVLSELKENVIWKWEDLENTPGN-SSNILYKNWLPQDDILAHPNTKLFITHAGK 368
            .:..:....|.:.|..:.:.|:|::..  ..|.| :.|.:...||||:|:|.||.|:.||||:|.
Mouse   313 EIPEKKAMEIAEALGRIPQTVLWRYTG--TRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGS 375

  Fly   369 GGITEAQYHGVPMVALPIFGDQPGNAALMEKSGYGLALDLLSITEDSLRDALKEVLENQKYKQAI 433
            .||.|...:|||||.:|:||||..||..||..|.|:.|::|.:|.|.|.:|||.|:.|:.||:.|
Mouse   376 HGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENI 440

  Fly   434 GQFSTLYRDRPMTAKQSVVFWTEYILRHQGAPNLQSPSVH-MNFIQLNNLDI--YALIVTILVLF 495
            .:.|:|::|||:......|||.||::||:|||:|: |:.| :.:.|.::||:  :.|.:.:.|:|
Mouse   441 MRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIVLTVVF 504

  Fly   496 VLLTRLVAKIVWNKFGGKAKISQTKKKQ 523
            ::. :..|......||||.::.::.|.:
Mouse   505 IVF-KCCAYGCRKCFGGKGRVKKSHKSK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	149/487 (31%)
		UDPGT	33..515	CDD:278624	155/514 (30%)
Ugt1a2	NP_038729.1	UDPGT	28..524	CDD:278624	158/527 (30%)
		Glycosyltransferase_GTB_type	43..>175	CDD:299143	31/142 (22%)
		egt	<261..505	CDD:223071	95/250 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840644
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H86211
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.740