DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37C2 and ugt-55

DIOPT Version :9

Sequence 1:	NP_001260516.1	Gene:	Ugt37C2 / 53513	FlyBaseID:	FBgn0040262	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_506073.2	Gene:	ugt-55 / 188072	WormBaseID:	WBGene00011452	Length:	512	Species:	Caenorhabditis elegans

Alignment Length:	516	Identity:	120/516 - (23%)
Similarity:	223/516 - (43%)	Gaps:	83/516 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 PSHLIIHMSVAKALVKAGHNVTVV-SMLKPKVTHK-DIHLIVVPMKEEQE----RIMEDQ----- 85
            |||:....::|..|.:.||||.|| ::|:..:::| |:.:|...:|.|..    :::.||
Worm    34 PSHVAFVANIANLLGQRGHNVVVVDNVLRSDISNKLDLKVIEKVVKVETSANVAKLLADQSIPIN 98

  Fly    86 ----MTEMAGQKNSLVSTMYRLLTSMDVMINAQAELL---SDPRFQRIYETKFDLMILGYFINDF 143
                ..|...||        :::..:.::...|.:.|   .:..|..:...:||..|...| :..
Worm    99 FWSMRNEPEEQK--------KVMKQLGIIFLEQCKYLVSKEETVFNELKHLEFDFGIHEVF-DIC 154

  Fly   144 QLGVAHKLKV--PVIINWMSAPVPAIDKYTGNPSELSYVPLMGTVATQPMGFLKRTENALKSLLF 206
            .:|:..||.:  .||::           .||          |..:..:.:|...:.::|  |:|.
Worm   155 GIGIFEKLGIRKSVILS-----------STG----------MRDIVNEALGISSQLQDA--SILS 196

  Fly   207 E------FIFVVFDYKLTRIYNDVFPEQDMPTLKELRKNIS----------MAFVGSHLISEGPI 255
            :      |..:..:.|....:.:.| |....||:.|.:..|          :.|:.:|.:::..
Worm   197 DYGNSIPFYGIRRNLKFHSAWRNFF-EVQSKTLEPLFETTSSFENLLRFSNLMFLNTHELADAH- 259

  Fly   256 RPLVPALIEIGGIQVKDKPDPLPKD-IDQFISNAKQGAVFLSLGSNVKSSTVRPEIVQIIFKVLS 319
            ||....:.|||||..| .|.||..: |:.|  |.....:.:|.|:...|..:..:....:.....
Worm   260 RPWSRRVHEIGGISFK-FPMPLKNEYINLF--NKYNSIILVSFGTTTPSFLMPEKYKNTLINTFQ 321

  Fly   320 ELKENV-IWKWE-DLENTPGN-SSNILYKNWLPQDDILAHPNTKLFITHAGKGGITEAQYHGVPM 381
            ...:.: |||:| |.|.|..| ..|:::|.:|||.|:|.....||||||.|:..:.|..:.....
Worm   322 RFPDFLFIWKYEKDDEFTQKNKKGNVVFKKFLPQVDLLESRKIKLFITHGGQNSLLETFHSNTRT 386

  Fly   382 VALPIFGDQPGNAALMEKSG--YGLALDLLSITEDSLRDALKEVLE-NQKYKQAIGQFSTLYRDR 443
            :..|:||||..||.:..::|  :.|..|.|: .|:.:..|:|:..| |:|....:.:.|:..::.
Worm   387 LITPLFGDQHRNAQIALENGLSHVLLKDQLA-NEELVYAAIKQGTESNKKLDDNLLKLSSNLKNA 450

  Fly   444 PMTAKQSVVFWTEYILRHQGAP-NLQ-SPSVHMNFIQLNNLDIYALIVTILVLFVLLTRLV 502
            ..|::...:...|.......:| |.: .|.::.:...|..||..|:....|:..:|:.:.:
Worm   451 KQTSENLFLDTVESTYTDNLSPLNFEFYPKLYSSDQILLYLDSIAMFTLTLLTMILIRKFL 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	112/478 (23%)
Ugt37C2	NP_001260516.1	UDPGT	33..515	CDD:278624	119/515 (23%)
ugt-55	NP_506073.2	UDPGT	35..>399	CDD:278624	95/400 (24%)
ugt-55	NP_506073.2	Glycosyltransferase_GTB_type	<247..>399	CDD:299143	47/155 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810