DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37C2 and ugt-30

DIOPT Version :9

Sequence 1:	NP_001260516.1	Gene:	Ugt37C2 / 53513	FlyBaseID:	FBgn0040262	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_506729.1	Gene:	ugt-30 / 187955	WormBaseID:	WBGene00011340	Length:	535	Species:	Caenorhabditis elegans

Alignment Length:	555	Identity:	146/555 - (26%)
Similarity:	250/555 - (45%)	Gaps:	76/555 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FLLLLGVVASTQGANILGLFSSHSPSHLIIHMSVAKALVKAGHNVT----VVSMLK------PKV 62
            |.|||    .:...|||....:.:.||......:|..|.:.|||||    ||::.|      .|:
Worm    10 FCLLL----YSNCLNILVYAPAFAASHSKFLGKLADTLTERGHNVTYLMPVVNIAKRDECKGVKI 70

  Fly    63 THKDIHLIVVPMKEE----------QERIMEDQMTEMAGQKNSLVSTMYRLLTSMDVMINAQAEL 117
            | ||:  ::|...|:          .:.|::...|......||  ..:::...| |:.|..:..|
Worm    71 T-KDV--VIVEAGEKMLSQKQADTPNDEILDVWWTVQMDSSNS--REIFQFFCS-DMKIACENFL 129

  Fly   118 LSDPRFQRIYETKFDLMILGYFINDFQLGVAHKLKV-PVIINWMSAPVPAIDKYTGNPSELSYVP 181
            .....|:.:....|||.||.. ::...||....|.: ..|:...|.....|..|.|.|.:.||||
Worm   130 SRRDIFEDMKARNFDLAILEP-VSACGLGFVKALGIEKTILASSSVFYDVILPYIGEPLDYSYVP 193

  Fly   182 LMGTVATQPMGFLKRTEN---------ALKSLLFEFIFVVFDYKLTRIYNDVFPEQDMPTLKELR 237
            ...:|..|.:...::.||         ||:.|        ||.:: .||..:. ..::...:.|.
Worm   194 SGYSVTGQELSLGEKFENWMVSREISIALEGL--------FDGEM-EIYRRLL-GHNLTNWRHLF 248

  Fly   238 KNISMAFVGSHLISEGPIRPLVPALIEIGGIQVK---DKPDPLPKDIDQFISNAKQGAVFLSLGS 299
            .:.|:.||.|:...:.| ||::...:.||||.|.   .|.|.|.::.:: :.|.:...:.:|.|:
Worm   249 PSASIFFVNSNPFFDFP-RPVLEKTVPIGGISVNMGVRKEDMLTEEWEK-VLNQRPHTMLVSFGT 311

  Fly   300 NVKSSTVRPEIVQIIFKVLSELKE------NV--IWKWEDLENTPGNS-SNILYKNWLPQDDILA 355
            .| .||..|:      |..|.|.|      ||  |||:|..:::..|. .||.:..|:||:::|.
Worm   312 LV-MSTHMPK------KWRSGLLEAFKSFPNVTFIWKYESDDHSFANGIDNIYFSKWVPQNELLN 369

  Fly   356 HPNTKLFITHAGKGGITEAQYHGVPMVALPIFGDQPGNAALMEKSGYGLALDLLSI-TEDSLRDA 419
            ......|::|.|.|.|.|..:.|.|.:.:|:|.||..||..:.:....:.|....: ..:.|:.|
Worm   370 DNRLTAFLSHGGLGSIMELAFSGKPALIIPVFADQTRNANTLARHRGAICLHKSQMKNTEVLKKA 434

  Fly   420 LKEVLENQKYKQAIGQFSTLYRDRPMTAKQSVVFWTEYILRHQGAPNLQSPSVHMNFIQLNNLDI 484
            .|.||.:..:|....:.:...|::|...|.:::.:||::......|.:.....|:|..|.:.:||
Worm   435 FKSVLFDASFKNNSLKLAATLRNQPNKPKDTLIKYTEFVGEFGPFPQMDPYGRHLNVFQKSFIDI 499

  Fly   485 YALIVTILVLFV-LLTRLVAKIVWNKFGGKAKISQ 518
            |.||:.:..:|| |:..::||::  ::..|:|.|:
Worm   500 YTLIIVVSSIFVALIFNVIAKLI--QYFIKSKSSE 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	130/501 (26%)
Ugt37C2	NP_001260516.1	UDPGT	33..515	CDD:278624	137/525 (26%)
ugt-30	NP_506729.1	UDPGT	21..529	CDD:278624	139/535 (26%)
ugt-30	NP_506729.1	Glycosyltransferase_GTB_type	<255..524	CDD:299143	78/279 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810