DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37C2 and ugt-34

DIOPT Version :9

Sequence 1:	NP_001260516.1	Gene:	Ugt37C2 / 53513	FlyBaseID:	FBgn0040262	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_505728.2	Gene:	ugt-34 / 185120	WormBaseID:	WBGene00009255	Length:	526	Species:	Caenorhabditis elegans

Alignment Length:	551	Identity:	140/551 - (25%)
Similarity:	229/551 - (41%)	Gaps:	69/551 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 HFVFLLLLGVVASTQGANILGLFSSHSPSHLIIHMSVAKALVKAGHNVTVVSMLKPKVTHKDIH- 68
            ||...||..:...|...|.|......:.||......:|..|.:||||||   .|.| :.|::..
Worm     7 HFSLFLLHLLPQLTLSYNYLVFCPLFAHSHHKFLAKIADTLTEAGHNVT---FLMP-IIHREYEN 67

  Fly    69 ---------LIVVPMKEEQERIME--DQMTEMAGQKNSL--------VSTMYRLLTSMDVMINAQ 114
                     ::.:...:|.|.|.:  |..|..   ||..        :...:|:.|.:..::...
Worm    68 VKYLEHTTDIVYIQPDKELEEIAQNADYSTFW---KNDFGILTFIPAIERFFRMFTKVHDILKKD 129

  Fly   115 AELLSDPRFQRIYETKFDLMI---LGYFINDFQLGVAHKLKVPVII-NWMSAPVPAIDKYTGNPS 175
            ..:|.:     :...|||.||   |.:..:.    :...|::..|. :|....:..:.:..|.||
Worm   130 LSVLDN-----LKNRKFDAMIFESLAFCAHP----IREYLEIKTIFPSWSMTHMTELSQAIGEPS 185

  Fly   176 ELSYVPLMGTVATQPMGFLKRTENALKSLLFEFIF---VVFDYKLTRIYNDVFPEQDMPTLKELR 237
            ..:::|:..:.....|.|.:|..|.|....|..||   .:..:|        :|.|.. ..||:.
Worm   186 SPTFLPITISPFGDKMTFKERLLNTLADFTFTHIFQPPTLTSFK--------YPHQTF-DFKEIL 241

  Fly   238 KNISMAFVGSHLISEGPIRPLVPALIEIGGIQVKD---KPDPLPKDIDQFISNAKQGAVFLSLGS 299
            ......|..|:...:.| ||.:...||||||.|..   :.:.||::.:. |.|.||..|.:|.||
Worm   242 SQAPFIFFNSNPFLDFP-RPTLTKTIEIGGISVNATLMRLEKLPEEYNT-ILNLKQQNVLISFGS 304

  Fly   300 NVKSSTVRPEIVQIIFKVLSELKE-NVIWKWED-----LENTPGNSSNILYKNWLPQDDILAHPN 358
            .::||.:..|....|.:|:..... ..|||:|:     .||.|    |..:..|:||..:||...
Worm   305 MLRSSEMPVEYKDTIAQVVRSFPSVTFIWKYENNNVEFAENLP----NFHFFKWVPQTALLADSR 365

  Fly   359 TKLFITHAGKGGITEAQYHGVPMVALPIFGDQPGNAALMEKSGYGLALDLLSITE-DSLRDALKE 422
            ...||||||.|.|.|..|.|.|.:.:|||.||..||.::.:....:.||...:.: |.||||:..
Worm   366 LSAFITHAGLGSINELSYIGKPAILVPIFADQLRNAKMLVRHNGSIELDKKDLGKFDVLRDAVDA 430

  Fly   423 VLENQKYKQAIGQFSTLYRDRPMTAKQSVVFWTEYILRHQGAPNLQSPSVHMNFIQLNNLDIYAL 487
            :|.::.|.......|.....:|.:....:|.:.|:..:....|:|......|:|.....:||...
Worm   431 ILNDKSYTNNAILLSQQLESQPFSPHDLLVKYAEFGAKFGELPSLDPHYRKMSFFSFFMIDIILF 495

  Fly   488 IVTILVLFVLLTRLVAKIVWNK-FGGKAKIS 517
            :.....:||.::..:.::.:.. |..|.||:
Worm   496 LTATFAIFVSISLYLFRVFFKSVFVRKEKIN 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	129/498 (26%)
Ugt37C2	NP_001260516.1	UDPGT	33..515	CDD:278624	131/519 (25%)
ugt-34	NP_505728.2	UDPGT	35..518	CDD:278624	129/513 (25%)
ugt-34	NP_505728.2	Glycosyltransferase_GTB_type	<248..500	CDD:299143	78/257 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810