DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37C2 and ugt-37

DIOPT Version :9

Sequence 1:	NP_001260516.1	Gene:	Ugt37C2 / 53513	FlyBaseID:	FBgn0040262	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_504811.2	Gene:	ugt-37 / 184293	WormBaseID:	WBGene00017332	Length:	528	Species:	Caenorhabditis elegans

Alignment Length:	525	Identity:	126/525 - (24%)
Similarity:	228/525 - (43%)	Gaps:	43/525 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VFLLLLGVVASTQGANILGLFS---SHSPSHLIIHMSVAKALVKAGHNVTVVSMLKPKVTHK--- 65
            :.:||..........|.| :||   .|  ||......:|..|.:||||||   ...|.:..|
Worm     3 ILILLFACFNVNFSYNFL-IFSPLFGH--SHTTFFAKIADTLSEAGHNVT---FFTPTIIRKFSK 61

  Fly    66 ------DIHLIVVPMKEEQERI---MEDQMTEMAGQKNSLVSTMYRLLTSMDVMINAQAELLSD- 120
                  ..|:|.:...|:.||.   |||.........:|.::.|:.::...:.|...||.:|..
Worm    62 INYVKHTKHVIHLEPSEKLERYGNQMEDVDISRFWTDDSSMAEMFPMIKLFNEMFAEQAFVLGQN 126

  Fly   121 -PRFQRIYETKFDLMILGYFINDFQLGVAHKLKVPVIINWMSAPV-PAIDKYTGNPSELSYVPLM 183
             .....:.|.|||:||...|. :....:...|::...|...|... |.:....|.|...|.|||.
Worm   127 LDVLDELKEMKFDVMIFERFA-ECAYPLLEYLEIETFIPSSSLLFDPNLLISIGEPRIPSTVPLP 190

  Fly   184 GTVATQPMGFLKRTENALKSLLFEFIFVVFDYKLTRIYNDVFPEQDMPTLKELRKNISMAFVGSH 248
            .:..|..|...:|..||:...:|..:....::|..|      |......::::....|.....|:
Worm   191 MSKFTDKMTMTERLLNAIAVPIFHSLLPTHEFKSFR------PPYQAIDIQKMEHLSSFILSNSN 249

  Fly   249 LISEGPIRPLVPALIEIGGIQVKDKPDPLPKDIDQF--ISNAKQGAVFLSLGSNVKSSTVRPEIV 311
            ...:.| ||.:...::||||.|..:...:.|..:::  |.:.:|..:.:|.||.:.|..:..|..
Worm   250 PYIDYP-RPTLEKNVQIGGISVDVENLKIHKVNEEWDRILDMRQKTILVSFGSVMLSKDMPVENK 313

  Fly   312 QIIFKVLSELKE-NVIWKWE--DLENTPGNSSNILYKNWLPQDDILAHPNTKLFITHAGKGGITE 373
            :|:.|.:.:..| ..|||:|  |.:.....:.||.:.:|:||..:||......|.||||.|.:.|
Worm   314 KILAKTMKQFPEVTFIWKYEFNDTDLFASETENIHFSSWVPQTALLADRRLTAFFTHAGLGSVNE 378

  Fly   374 AQYHGVPMVALPIFGDQPGNAALMEKSGYGLALDLLSI-TEDSLRDALKEVLENQKYKQAIGQFS 437
            ..|.|.|.:..|||.||..||.::.:....:.:....: ..:.:...|:.:|.:..|:.:..:.:
Worm   379 VSYLGKPSIMCPIFADQMRNAKMLARHNGSIEISKYDLGNGEKIEKTLRTILFDDSYRLSAEKLA 443

  Fly   438 TLYRDRPMTAKQSVVFWTEYILRHQGAPNLQSPSVHMNFIQLNNLDIYALIV-----TILVLFVL 497
            ....::|:..|:.::...|:..:....|:|...|..::|::...:|:.|:::     .::|||.:
Worm   444 HQLANQPVKPKELLLRHAEFAAQFGRLPSLDPYSRQLSFVEYFLIDVAAILIFSSLLIVVVLFQI 508

  Fly   498 LTRLV 502
            :.||:
Worm   509 IKRLI 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	116/483 (24%)
Ugt37C2	NP_001260516.1	UDPGT	33..515	CDD:278624	119/496 (24%)
ugt-37	NP_504811.2	Glycosyltransferase_GTB_type	1..504	CDD:299143	121/514 (24%)
ugt-37	NP_504811.2	UDPGT	37..510	CDD:278624	115/483 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810