DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37C2 and ugt-7

DIOPT Version :9

Sequence 1:	NP_001260516.1	Gene:	Ugt37C2 / 53513	FlyBaseID:	FBgn0040262	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_504343.2	Gene:	ugt-7 / 182577	WormBaseID:	WBGene00015739	Length:	530	Species:	Caenorhabditis elegans

Alignment Length:	528	Identity:	128/528 - (24%)
Similarity:	227/528 - (42%)	Gaps:	84/528 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 HSPSHLIIHMSVAKALVKAGHNVTV-----VSMLKPK--VTHKDIHLIVVPMKEEQERIMEDQMT 87
            :|.||:....::|..|...||.|.|     |..|:.|  :.:.||.:|             :...
Worm    25 YSYSHVKFMSNIADTLADHGHEVVVFQQQIVEALRDKKVIKNPDIKII-------------NYEA 76

  Fly    88 EMAGQ---KNSLVSTMYRLLTSMDVMINAQAELLSDPRFQ-------RIYETK----------FD 132
            ..||:   :|...|::.:..|:......:.|:..::...:       :::|.|          ||
Worm    77 NTAGKEFYRNRPKSSVTKYWTTNQAANPSAADQFAEAMSKDLEHMCLQVFEDKSLHTMLKSEHFD 141

  Fly   133 LMI------LGYFINDFQLGVAHKLKVP-VIINWMSAPVPAIDKYTGNPSELSYVPLMGTVATQP 190
            :::      .|.::.|:       ||:| .|:...|:.:..:....|.||.|:::|...:...:.
Worm   142 VLLAEPFDPCGLYLGDY-------LKIPSTIVAMASSRIDPVQWALGQPSGLNFIPGPDSKYGEE 199

  Fly   191 MGFLKRTENALKSLLFEFIFVVFDYKLTRIYNDVFPEQDMPTLKELRKNI-------SMAFVGSH 248
            .|...|..|.       ::|.:.......:|.::..:....|..|:| ||       :..|..|:
Worm   200 SGVWDRINNV-------WMFFMRTRMFRAVYWNLLDKLRFKTGLEIR-NIDEIVAESAYLFYNSN 256

  Fly   249 LISEGPIRPLVPALIEIGGIQVKD---KPDPLPKDIDQFISNAKQGAVFLSLGSNVKSSTVRPEI 310
            ...:.|. |.:...:.|||..:..   |.:.||:::...:.. :...||:|.||.::|:.:..|.
Worm   257 PYLDFPF-PSLTKCVPIGGFSMNTTNWKSENLPENLKNILQK-RPNTVFISFGSVIRSADMPQEY 319

  Fly   311 VQIIFKVLSELKENV--IWKWEDL--ENTPGN-SSNILYKNWLPQDDILAHPNTKLFITHAGKGG 370
            ...|.:| ::|..:|  |||:||.  |...|| ..|:....||||..:||.....|||||.|.|.
Worm   320 KNAIIEV-TKLMSDVTFIWKYEDEKDEEMRGNIPENVHLMKWLPQPALLADSRVSLFITHGGLGS 383

  Fly   371 ITEAQYHGVPMVALPIFGDQPGNAALMEKSGYGLALDLLSITE-DSLRDALKEVLENQKYKQAIG 434
            |.|..|.|.|.:.:|:|.|||.|..::.:.|.........::. ..|:..::.:::|.||.....
Worm   384 IMEVAYSGKPAIVIPLFFDQPMNGEMLRRHGGAEVYSKFELSNAKKLKKVIQNMIQNPKYLANAK 448

  Fly   435 QFSTLYRDRPMTAKQSVVFWTEYILRHQGAPNLQSPSVHMNFIQLNNLDIYALIVTILVLFVLLT 499
            :.|.|.:.:|:...:.:|...|:....:..|.|...|.|:||.|...|||   :.|:|:||:|..
Worm   449 KLSNLLQKQPINPIERLVKHAEFAAEFKKLPELDPYSRHLNFFQFFFLDI---VATLLILFMLSA 510

  Fly   500 RLVAKIVW 507
            ..|..|.:
Worm   511 LFVYWITY 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	112/486 (23%)
Ugt37C2	NP_001260516.1	UDPGT	33..515	CDD:278624	127/525 (24%)
ugt-7	NP_504343.2	egt	1..477	CDD:223071	111/482 (23%)
ugt-7	NP_504343.2	UDPGT	27..521	CDD:278624	127/526 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810