DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37C2 and ugt-63

DIOPT Version :9

Sequence 1:	NP_001260516.1	Gene:	Ugt37C2 / 53513	FlyBaseID:	FBgn0040262	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_504369.1	Gene:	ugt-63 / 182223	WormBaseID:	WBGene00015449	Length:	506	Species:	Caenorhabditis elegans

Alignment Length:	530	Identity:	111/530 - (20%)
Similarity:	209/530 - (39%)	Gaps:	114/530 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 HMSVAKALVKAGHNVTVVSMLKPKVT---------HKDIHLIVVPMKEEQERI---MEDQMTEMA 90
            |...|:||      :||:...:...|         .||.|...:.....::.|   |:::..:|:
Worm    21 HAEAARAL------LTVMDQGRSHATSINTFMHRLQKDNHTTALEFAHFRQDIDFGMDERFIDMS 79

  Fly    91 GQKNSLVSTMY-RLLTSMDVMINAQA-----------ELLSDPR---FQRIYETKFDL------- 133
            |.:|...|..: ::....|.....||           .:|...|   |:.:|| .:|:
Worm    80 GFQNPFESPDFDKIAFEEDYSFIHQAVAYGFGSQTCNNILKHRRERFFEILYE-DWDIYLSDSLF 143

  Fly   134 MILGYFINDFQLGVAHKLKVPVIINWMSAPVPAIDKYTGNPSELSYVPLMGTVATQPMGFLKRTE 198
            .|.||       |:|                    :.:|.|..:.:...:........||.:...
Worm   144 AICGY-------GMA--------------------EISGKPHVMMHSTDLEAAQGSFKGFSRNYA 181

  Fly   199 NALKSLLFEFIFVVFDYKLTRIYNDVFPEQDMPTLKELRKNISMAFVGSHLISEGPIRPLVP--- 260
            ..:.|.|   .|.:.:|.::..|:.|:...|.     ....|..|:|| :...:..:|.::|
Worm   182 TFVPSNL---PFSMLNYTVSNYYHRVWAAYDW-----FGSFIFTAYVG-NFAQKWALRSIIPFPY 237

  Fly   261 -ALIEIG---------------------------GIQVKDKPDPLPKDIDQFISNAK-QGAVFLS 296
             :..|..                           |...|:...||..:...||.:.| :|.:.::
Worm   238 FSFAEYNRRSSFTFTDMPDSLFPPASRTNDFFSFGAYCKESSKPLDLEFKTFIEHPKSKGTILIA 302

  Fly   297 LGSNVKSSTVRPEIVQIIFKVLSELKE-NVIWKWEDLENTPGNSSNILYKNWLPQDDILAHPNTK 360
            .|:.:...............|::.|.| .:||..:. |..||...::...:|:||:.||.|..|.
Worm   303 FGTFIDWRKAPKNYYDAFATVVNRLSEYRIIWSMKG-ERPPGLKKHVKTSSWVPQNQILHHNKTV 366

  Fly   361 LFITHAGKGGITEAQYHGVPMVALPIFGDQPGNAALMEKSGYGLALDLLSITEDSLRDALKEVLE 425
            ||::|.|.....|......|.:.:|:||:|..||.|:::.|:...::...|..|.|...::||||
Worm   367 LFLSHGGLKSTKEVICSATPTIFVPMFGEQTRNAWLIKEKGFARIMNKFKINVDELDTHMREVLE 431

  Fly   426 NQKYKQAIGQFSTLYRDRPMTAKQSVVFWTEYILRHQG-APNLQSP-SVHMNFIQLNNLDIYALI 488
            :..|:|...:|.|.|.|:|:.......|....::::.| .|:...| |:.:::..:.|:|: .::
Worm   432 HPNYQQNANKFLTYYMDQPIPTLDEGAFKFNRLVKYGGKMPSHFYPKSLDLSYFTVLNVDL-LIV 495

  Fly   489 VTILVLFVLL 498
            |.|::|:::|
Worm   496 VPIMMLYLVL 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	103/496 (21%)
Ugt37C2	NP_001260516.1	UDPGT	33..515	CDD:278624	111/530 (21%)
ugt-63	NP_504369.1	Glycosyltransferase_GTB_type	<276..500	CDD:299143	60/225 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010