DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37C2 and ugt-64

DIOPT Version :9

Sequence 1:	NP_001260516.1	Gene:	Ugt37C2 / 53513	FlyBaseID:	FBgn0040262	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_503978.1	Gene:	ugt-64 / 178774	WormBaseID:	WBGene00015577	Length:	501	Species:	Caenorhabditis elegans

Alignment Length:	540	Identity:	114/540 - (21%)
Similarity:	210/540 - (38%)	Gaps:	153/540 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 AKALV----KAGHNVTVVSMLKPKVTHKDIHLIVVPM---KEEQERIMEDQMTEMAGQKNSLVST 99
            ||.|:    :...:.|.::.|..::...| |...:.|   |.:.:..||::...|:|.:|:.:|.
Worm    20 AKVLLTVMDQGRSHATSITPLMHRLQKND-HTTALEMATYKPDIDFGMEERFINMSGFENNFISK 83

  Fly   100 MY--------------------------RLL------------TSMDVMIN---------AQAEL 117
            .:                          |:|            .:.|:.::         |.||:
Worm    84 DFFKIAFEDEFTFVHQAVPFIFGSISCDRILKHQKNRYLEIANENWDLFLSDSLFSPCGYAMAEI 148

  Fly   118 LSDPR-----------------FQRIYETKFDLMI---LGYFINDFQLGVAHKLKVPVIINWMSA 162
            ...|.                 |.|.|.    :|:   |.|.:::|.: ..:..:|...::|..:
Worm   149 TGKPHVMMHSSDVESAHGSFKGFSRNYA----IMVPNFLPYSMSNFTI-EKYWHRVVSTVDWFGS 208

  Fly   163 PVPAIDKYTGNPSELSYVPLMGTVATQPMGFLKRTENALKSLL-FEFIFVVFDYKLTRIYNDVFP 226
            ..                 :.|.||    ||.::.  ||:|:: |.| |..:||.    ....|.
Worm   209 AF-----------------ITGAVA----GFAQKW--ALRSIIPFPF-FSFYDYN----RRSSFS 245

  Fly   227 EQDMPTLKELRKNISMAFVGSHLISEGPIRPLVPALIEIGGIQVKD----------KPDPLPKDI 281
            ..|||.                        ||.|.     |.:..|          :...|.:|.
Worm   246 FTDMPD------------------------PLYPV-----GARTNDYFSFGTYCTAQKKVLDEDW 281

  Fly   282 DQFISNAK-QGAVFLSLGSNVKSSTVRPEIVQIIFKVLSELKE-NVIWKWEDLENTPGNSSNILY 344
            :||:|:.| :|.:.::.|:.:.......|..:|....|:.|.| .|||..:. :...|...::..
Worm   282 EQFVSDPKSKGTILVAFGTIIDWRFAPEEKFEIFLNTLNRLTEYRVIWSMKG-DRPKGLGEHVKI 345

  Fly   345 KNWLPQDDILAHPNTKLFITHAGKGGITEAQYHGVPMVALPIFGDQPGNAALMEKSGYGLALDLL 409
            .:|:||..||.|..|.||::|.|...:.||.....|.:.:|:|.:|..||.|.:..|:...|:..
Worm   346 SSWVPQQQILNHKKTVLFLSHGGLKSVKEAVCSATPSLFMPMFAEQMRNAWLAKSKGFARILNKF 410

  Fly   410 SITEDSLRDALKEVLENQKYKQAIGQFSTLYRDRPMTAKQSVVFWTEYILRHQG-APNLQSP-SV 472
            .::|..|.:.::||:|::.|:....||.:.:.|:||.|.....|..|.:.::.| .|....| ::
Worm   411 HLSEQYLENHIREVVEHKSYQIQAEQFLSTFTDQPMPALDEAAFKFERLFKYNGKMPKFFYPKTI 475

  Fly   473 HMNFIQLNNLDIYALIVTIL 492
            .::::...||||:.::..:|
Worm   476 DLSYLTALNLDIWVIVPLVL 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	108/512 (21%)
Ugt37C2	NP_001260516.1	UDPGT	33..515	CDD:278624	114/540 (21%)
ugt-64	NP_503978.1	Glycosyltransferase_GTB_type	<271..468	CDD:299143	54/197 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010