Protein Alignment Ugt37C2 and UGT2B11

DIOPT Version :9

• Sequence 1: NP_001260516.1
• Gene: Ugt37C2 / 53513
• FlyBaseID: FBgn0040262
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_001064.1
• Gene: UGT2B11 / 10720
• HGNCID: 12545
• Length: 529
• Species: Homo sapiens
• Alignment Length: 522
• Identity: 147/522 - (28%)
• Similarity: 261/522 - (50%)
• Gaps: 70/522 - (13%)

  Fly    33 SHLIIHMSVAKALVKAGHNVTVV-------------SMLKPKV-----THKDIHLIVVPMKEEQE 79
            ||.:...::.|.||:.||.|||:             |.||.:|     |..:...|::...:...
Human    34 SHWMNMKTILKELVQRGHEVTVLASSASILFDPNDASTLKFEVYPTSLTKTEFENIIMQQVKRWS 98

  Fly    80 RIMEDQMTEMAGQKNSLVSTMYRLLTSMDVMINAQAELLSDPR-FQRIYETKFDLMILGYFINDF 143
            .|.:|.......|:..::..:|      |:..|...:::|:.: .:::.|::||::.....   |
Human    99 DIRKDSFWLYFSQEQEILWELY------DIFRNFCKDVVSNKKVMKKLQESRFDIVFADAV---F 154

  Fly   144 QLG--VAHKLKVPVIINWMSAPVPAIDKYTGN---PSELSYVPLMGTVATQPMGFLKRTENALKS 203
            ..|  :|..|.:..:.:....|...|::::|.   |.  ||:|::.:..:..|.|::|.:|.:..
Human   155 PCGELLAALLNIRFVYSLRFTPGYTIERHSGGLIFPP--SYIPIVMSKLSDQMTFMERVKNMIYV 217

  Fly   204 LLFEFIFVVFDY-KLTRIYNDVF--PEQDMPTLKE----LRKNISMAFVGSHLISEGPIRPLVPA 261
            |.|:|.|.:.|. |..:.|::|.  |.....|:.:    |.:| |.:|...|        |.:|.
Human   218 LYFDFWFQMSDMKKWDQFYSEVLGRPTTLFETMGKADIWLMRN-SWSFQFPH--------PFLPN 273

  Fly   262 LIEIGGIQVKDKPDPLPKDIDQFI-SNAKQGAVFLSLGSNVKSSTVRPEIVQIIFKVLSELKENV 325
            :..:||...| ...||||::::|: |:.:.|.|..||||.:.:.|.  |...:|...|:::.:.|
Human   274 VDFVGGFHCK-PAKPLPKEMEEFVQSSGENGVVVFSLGSVISNMTA--ERANVIATALAKIPQKV 335

  Fly   326 IWKWEDLENTPGNSSNI------LYKNWLPQDDILAHPNTKLFITHAGKGGITEAQYHGVPMVAL 384
            :|:::      ||..:.      ||| |:||:|:|.||.|:.||||.|..||.||.|||:|||.:
Human   336 LWRFD------GNKPDALGLNTRLYK-WIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGI 393

  Fly   385 PIFGDQPGNAALMEKSGYGLALDLLSITEDSLRDALKEVLENQKYKQAIGQFSTLYRDRPMTAKQ 449
            |:|.|||.|.|.|:..|..:.||..:::...|.:|||.|:.:..||:.|.:.|.:..|:|:....
Human   394 PLFFDQPDNIAHMKAKGAAVRLDFNTMSSTDLLNALKTVINDPLYKENIMKLSRIQHDQPVKPLD 458

  Fly   450 SVVFWTEYILRHQGAPNLQSPSVHMNFIQLNNLDIYA-LIVTILVLFVLLTRLVAKIVWNKFGGK 513
            ..|||.|:::.|:||.:|:..:..:.:.|.::||:.. |:..:..:..::|:......| ||..|
Human   459 RAVFWIEFVMPHKGAKHLRVAAHDLTWFQYHSLDVIGFLLACVATVIFIITKFCLFCFW-KFARK 522

  Fly   514 AK 515
            .|
Human   523 GK 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	136/471 (29%)
		UDPGT	33..515	CDD:278624	146/520 (28%)
UGT2B11	NP_001064.1	UDPGT	24..525	CDD:278624	147/522 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150518
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740