DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37C2 and ugt5b2

DIOPT Version :9

Sequence 1:	NP_001260516.1	Gene:	Ugt37C2 / 53513	FlyBaseID:	FBgn0040262	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_001170970.2	Gene:	ugt5b2 / 100415799	ZFINID:	ZDB-GENE-100406-4	Length:	531	Species:	Danio rerio

Alignment Length:	523	Identity:	139/523 - (26%)
Similarity:	243/523 - (46%)	Gaps:	78/523 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GVHFVFLLLLGVVASTQGANILGL-------FSSHSPSHLIIHMSVAKALVKAGHNVTVVSMLKP 60
            |.|:|.:.:|....|.:|.::..:       ....||.:..|::.     .|.|:|..|:.....
Zfish    36 GSHWVNMNILVEALSAKGHDVTVMRTASSCYIKEFSPHYTSINLK-----SKGGYNKEVLEQFAS 95

  Fly    61 KVTH--KD----IHL-IVVPMKE------EQERIMEDQMTEMAGQKNSLVSTMYRLLTSMDVMIN 112
            ::.|  :|    .|| :...|.:      |.||.|...|.|......||....|.|
Zfish    96 RIMHILRDGSTWGHLKLQADMWQSFLKIFEAEREMIVNMIEDQQLMQSLKDAKYDL--------- 151

  Fly   113 AQAELLSDPRFQRIYETKFDLMILGYFINDFQLGVAHKLKVPVIIN--WMSAPVPAIDKYTGNPS 175
                :|:||..       |..:|||           |.||:|::.|  |......   .::..||
Zfish   152 ----ILTDPNM-------FGGVILG-----------HYLKLPMVYNVRWAGYNEA---HFSIAPS 191

  Fly   176 ELSYVPLMGTVATQPMGFLKRTENALKSLLFEFIFVVFDYKLT-RIYNDVFPEQDMPTLKELRKN 239
            .|||||:.....:..|.||:|..|.:.     :||:.....|. ...||...|:.:.........
Zfish   192 PLSYVPMPSLELSDRMSFLQRVYNVVM-----YIFIEIGAALVISPINDALAERFIGPGTSFLSL 251

  Fly   240 ISMAFVGSH---LISEGPIRPLVPALIEIGGIQVKDKPDPLPKDIDQFI-SNAKQGAVFLSLGSN 300
            :..|.:..|   .:.|.| ||.:|.:|.:.|.|.|.. .|||:|::.|: |:...|.:.:|||:.
Zfish   252 VQGADLWLHRVDFVFEYP-RPTMPNVIYMAGFQCKPS-KPLPQDLEDFVQSSGDHGVIIMSLGTL 314

  Fly   301 VKSSTVRPEIVQIIFKVLSELKENVIWKWEDLE-NTPGNSSNILYKNWLPQDDILAHPNTKLFIT 364
            :  ..:..::.:.|.:..:||.:.:||:::... :..||  |.|..:|:||:|:|.||.|:.|:.
Zfish   315 I--DKLPDDVAEAIAEAFAELPQKIIWRYKGKRPSALGN--NTLIMDWMPQNDLLGHPKTRAFVA 375

  Fly   365 HAGKGGITEAQYHGVPMVALPIFGDQPGNAALMEKSGYGLALDLLSITEDSLRDALKEVLENQKY 429
            |.|..||.||.|||||::...:..|||.|.:.|...|....:|..::.::|....:||||.:..|
Zfish   376 HGGTNGIQEAIYHGVPIIGFGLIFDQPDNLSKMRVRGAAKNVDFATMNKESFLTTVKEVLYDPSY 440

  Fly   430 KQAIGQFSTLYRDRPMTAKQSVVFWTEYILRHQGAPNLQSPSVHMNFIQLNNLDIYALIVTILVL 494
            ::.:.:.|.|::|.|:....:.:||.|:::||:||.:|::.|..|.:...:::|:..::::.:.|
Zfish   441 RENMQRLSRLHKDVPVKPLDNAIFWIEFVMRHKGAAHLRTESYKMPWYSYHSVDVILVLISAVSL 505

  Fly   495 FVL 497
            .:|
Zfish   506 IIL 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	133/491 (27%)
Ugt37C2	NP_001260516.1	UDPGT	33..515	CDD:278624	131/486 (27%)
ugt5b2	NP_001170970.2	egt	12..501	CDD:223071	137/514 (27%)
ugt5b2	NP_001170970.2	UDPGT	27..525	CDD:278624	139/523 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584563
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.740