Protein Alignment Ugt37E1 and Ugt1a6a

DIOPT Version :10

• Sequence 1: NP_652628.2
• Gene: Ugt37E1 / 53512
• FlyBaseID: FBgn0040261
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_659545.2
• Gene: Ugt1a6a / 94284
• MGIID: 2137698
• Length: 531
• Species: Mus musculus
• Alignment Length: 572
• Identity: 157/572 - (27%)
• Similarity: 263/572 - (45%)
• Gaps: 110/572 - (19%)

  Fly     8 GFLIAFLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALADRGHNITVVTQMKPKLATHENI 72
            |||...|.:::.    |..:|.|  ....||.:....:::.|::|||:|.|:.         ..:
Mouse    14 GFLFLVLWASVL----GDKLLVV--PQDGSHWLSMKEIVEHLSERGHDIMVLV---------PEV 63

  Fly    73 TVIIAPPTEERQRYIKEYMAEVSNEKPSFWETMVKAIVQSSNQLEGQYEFMTHPN---------- 127
            .:::.                    :..::...:.::..|..:|  |..|.|..|
Mouse    64 NLLLG--------------------ESKYYRRKIFSVTYSLEEL--QTRFRTFGNNHFLPGASLM 106

  Fly   128 --VKEIYENPKIKFDLVF---LGLMANTYQLGIAAKLK-----------CPVIIS-WVGIPLPF- 174
              ::| |.|..|..|:.|   ..|:.::..|....:.|           |.||:: ::.:|..:
Mouse   107 GPLRE-YRNNMIVVDMFFSNCQSLLKDSATLSFLRENKFDALFTDPAMPCGVILAEYLNLPSVYL 170

  Fly   175 -------MDTIVGNVNDP-SYVPTVNVALNAGQKTMDFGLRFVNFFKYAIMCVFETVLDYKMNQF 231
                   ::.::|....| ||||......:   ..|.|..|..||    |:.:.|..|.|.:...
Mouse   171 FRGFPCSLEHMLGQSPSPVSYVPRFYTKFS---DHMTFPQRLANF----IVNILENYLYYCLYSK 228

  Fly   232 YERAFANEL-----EFPNYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPK 291
            || ..|::|     ..|:.|:.    ||....|....|.| ||.:|..|.:|||..|::. .|.:
Mouse   229 YE-IIASDLLKRDVSLPSLHQN----SLWLLRYDFVFEYP-RPVMPNMIFLGGINCKKKG-KLTQ 286

  Fly   292 ELAKFLDKADE-GAIFFSLGTNVNTNTFRPDTVDI-LYKVLSKLPQRVIWKWEDLKNKPGN-ASN 353
            |...:::.:.| |.:.||||:.|:.   .|:...: :.:.|.::||.|:|::..  .:|.| |.|
Mouse   287 EFEAYVNASGEHGIVVFSLGSMVSE---IPEKKAMEIAEALGRIPQTVLWRYTG--TRPSNLAKN 346

  Fly   354 IFFGNWLPQDDILAHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWL 418
            .....||||:|:|.||.|:.||||:|..|:.|...:|||||.:|:||||..||:.|...|.|..|
Mouse   347 TILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTL 411

  Fly   419 DILTMTEHELEQTIREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHLQSPL 483
            ::|.||..:||..::.|:.|.:|:|.|.:.|:|::|||:......::|.|||:||:||.||:...
Mouse   412 NVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAA 476

  Fly   484 IHTKFVARNNLDVYGVVLLVSLLLIVTIKFLFRKILNVAIGYGSQRKAVANK 535
            ....:...::|||.|.:|.:    ::|:.|:..|    ...||. ||....|
Mouse   477 HDLTWYQYHSLDVIGFLLAI----VLTVVFIVFK----CCAYGC-RKCFGGK 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	GT1_Gtf-like	25..466	CDD:340817	129/484 (27%)
Ugt1a6a	NP_659545.2	UDPGT	27..522	CDD:278624	152/555 (27%)