Protein Alignment Ugt37E1 and ugt5a2

DIOPT Version :10

• Sequence 1: NP_652628.2
• Gene: Ugt37E1 / 53512
• FlyBaseID: FBgn0040261
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001070191.3
• Gene: ugt5a2 / 767756
• ZFINID: ZDB-GENE-061103-373
• Length: 524
• Species: Danio rerio
• Alignment Length: 566
• Identity: 159/566 - (28%)
• Similarity: 263/566 - (46%)
• Gaps: 104/566 - (18%)

  Fly     5 TKIGFLIAFLLSTMTQS-SGGANILGVFGTHSPSHVIVHMAVM-KALADRGHNITVVT-----QM 62
            |.:|..:  ||..:::| :|...::.|.|:|     .|:|.|: ..|..|||:||||.     .:
Zfish     5 THLGLFL--LLCVLSRSYAGKLLVVPVEGSH-----WVNMKVLIVELHSRGHSITVVRGSSSWYI 62

  Fly    63 KPKLATHENITVIIAPPTEERQRYIKEYMAEVSNEKPSFWETMVKAIVQSSNQLEGQYEFMTHPN 127
            :.:...:.:|||......::.......::.::..:..|||..|..|        :....|:|..:
Zfish    63 EEQSPLYTSITVDNGVFDDDFMETFLPHLLKIQRQGKSFWNEMALA--------DEMIHFVTETH 119

  Fly   128 VKE------IYENPKI-------KFDLVFLGLMANTYQLGI--AAKLKCPVI--ISWVGIPLPFM 175
            .:.      ::||..:       .:|:|   |....|..|:  |.:|..|::  :.|
Zfish   120 KQSCNMTAILFENETLMNSLKDAAYDVV---LTDPAYGSGVLLAHRLGLPLVYNVRW-------- 173

  Fly   176 DTIVGNVN-----DP-SYVPTVNVALNAGQKTMDFGLRFVNFFKYAIMCVFETVLDYKMN----- 229
             |:.|..:     .| ||||...:.|.   ..|.|..|.:|...| ||..::    |..|
Zfish   174 -TVYGEAHFDIAPSPLSYVPVSGLQLT---DKMTFSQRVMNMMTY-IMIRYK----YSKNFGSPY 229

  Fly   230 -QFYERAFANELEFPNYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPKEL 293
             :..::.|...:   |:..:.:...|.........|.| |||:|..:.:||.|.| .|.|||.:|
Zfish   230 QELTQKYFGPNV---NFFSLLQDADLWLMRNDFTFEFP-RPTMPNVVYMGGFQCK-PAKPLPGDL 289

  Fly   294 AKFLDKADE-GAIFFSLGT-------NVNTNTFRPDTVDILYKVLSKLPQRVIWKWEDLKNKPGN 350
            .:|:..:.| |.|..||||       .:|         |.:....::|||:|||::..  .:|.|
Zfish   290 EEFVQSSGEHGVIMMSLGTVFGQLLSELN---------DEIAAAFAQLPQKVIWRYTG--PRPAN 343

  Fly   351 -ASNIFFGNWLPQDDILAHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGF 414
             .:|....|||||:|:|.||.||||:.|.|..|:.||.|||||:|.||:..||..|...|...|.
Zfish   344 LGNNTLIVNWLPQNDLLGHPKTKLFVAHGGTNGLQEAIYHGVPIVGLPLAFDQPDNLSRMRAKGT 408

  Fly   415 GRWLDILTMTEHELEQTIREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHL 479
            .:.::..|:......:.::|||.||:|||.:.|.|.|:.|:|:......|:|.|:|:|::||.||
Zfish   409 AKIVEFATLDRAVFLEALKEVLHNPSYRENMQKLSKLHHDQPMKPLDRAIFWIEFVMRNKGAPHL 473

  Fly   480 QSPLIHTKFVARNNLDVYGVVLLVSLLLIV----TIKF----LFRK 517
            ::......::...::||...::|:.|:.::    |:|:    ||||
Zfish   474 RTQSFRMSWIEYQSIDVILTLMLMVLVFVLLTAYTMKYFCLCLFRK 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	GT1_Gtf-like	25..466	CDD:340817	135/484 (28%)
ugt5a2	NP_001070191.3	None