Protein Alignment Ugt37E1 and UGT8

DIOPT Version :9

• Sequence 1: NP_652628.2
• Gene: Ugt37E1 / 53512
• FlyBaseID: FBgn0040261
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001121646.2
• Gene: UGT8 / 7368
• HGNCID: 12555
• Length: 541
• Species: Homo sapiens
• Alignment Length: 539
• Identity: 150/539 - (27%)
• Similarity: 229/539 - (42%)
• Gaps: 125/539 - (23%)

  Fly    37 SHVIVHMAVMKALADRGHNITVVTQMKPKLATHENITVIIAPPTEERQRYIKEYMAEVSNEKPS- 100
            ||:.:...:..||.:|||:...:......:|...:.::         |||            |.
Human    33 SHMYIFKTLASALHERGHHTVFLLSEGRDIAPSNHYSL---------QRY------------PGI 76

  Fly   101 FWETMVKAIVQSS--NQLEGQ------YEFMTH---------PNVKEIYENPKIKFDLV------ 142
            |..|...|.:||.  |...|:      ::.:.|         .|...|....|.||||:
Human    77 FNSTTSDAFLQSKMRNIFSGRLTAIELFDILDHYTKNCDLMVGNHALIQGLKKEKFDLLLVDPND 141

  Fly   143 --------FLGLMANTYQLGIAAKLKCPVIISW----VGIPLPFMDTIVGNVNDPSYVPTVNVAL 195
                    .||:....:..|:           |    ||.|.|.           :|||..|..|
Human   142 MCGFVIAHLLGVKYAVFSTGL-----------WYPAEVGAPAPL-----------AYVPEFNSLL 184

  Fly   196 NAGQKTMDFGLRFVNFFKYAIMCVFETVLDYKMNQFYERAFANELEFPNYHEMKRRVSLL----F 256
            .   ..|:...|..|...|.|                .|...:.|..|.|..:.::.:||    .
Human   185 T---DRMNLLQRMKNTGVYLI----------------SRLGVSFLVLPKYERIMQKYNLLPEKSM 230

  Fly   257 YN-YHSAS----------EGPIRPTVPQSIEIGGIQVKEQADPLPKELAKFLDKADE-GAIFFSL 309
            |: .|.:|          |.| |||:|..:.:|||..| .|.|||::|.::::.|:| |.:..|.
Human   231 YDLVHGSSLWMLCTDVALEFP-RPTLPNVVYVGGILTK-PASPLPEDLQRWVNGANEHGFVLVSF 293

  Fly   310 GTNVNTNTFRPDTVDILYKVLSKLPQRVIWKWEDLKNKP-GNASNIFFGNWLPQDDILAHPNTKL 373
            |..|  .....|..:.|...|.:|||:|||::...|.|. ||.:.:.  .||||:|:|.|...|.
Human   294 GAGV--KYLSEDIANKLAGALGRLPQKVIWRFSGPKPKNLGNNTKLI--EWLPQNDLLGHSKIKA 354

  Fly   374 FITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHELEQTIREVLGN 438
            |::|.|...:.|..|||||:|.:|:|||.......:...|.|..|:..|:||.||.:.:.:|:.|
Human   355 FLSHGGLNSIFETIYHGVPVVGIPLFGDHYDTMTRVQAKGMGILLEWKTVTEKELYEALVKVINN 419

  Fly   439 PAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHLQSPLIHTKFVARNNLDVYGVVLLV 503
            |:||:...|.|.:::|:|.......|||.:|::||.||.||::.:....|.....||:..|:||.
Human   420 PSYRQRAQKLSEIHKDQPGHPVNRTIYWIDYIIRHNGAHHLRAAVHQISFCQYFLLDIAFVLLLG 484

  Fly   504 SLLLIVTI----KFLFRKI 518
            :.||...:    ||::|||
Human   485 AALLYFLLSWVTKFIYRKI 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	egt	7..475	CDD:223071	133/490 (27%)
		YjiC	27..448	CDD:224732	123/463 (27%)
UGT8	NP_001121646.2	Glycosyltransferase_GTB-type	21..502	CDD:415824	147/536 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150683
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840