Protein Alignment Ugt37E1 and UGT2B7

DIOPT Version :9

• Sequence 1: NP_652628.2
• Gene: Ugt37E1 / 53512
• FlyBaseID: FBgn0040261
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001065.2
• Gene: UGT2B7 / 7364
• HGNCID: 12554
• Length: 529
• Species: Homo sapiens
• Alignment Length: 544
• Identity: 153/544 - (28%)
• Similarity: 252/544 - (46%)
• Gaps: 62/544 - (11%)

  Fly     2 IEYTKIGFLIAFLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALADRGHNITVVTQMKPKL 66
            :::|.:..||..   :...|||....:.|:.... ||.:....::..|..|||.:||:......|
Human     3 VKWTSVILLIQL---SFCFSSGNCGKVLVWAAEY-SHWMNIKTILDELIQRGHEVTVLASSASIL 63

  Fly    67 ATHEN---ITVIIAPPT---EERQRYIKEYMAEVSN-EKPSFWETMVKAIVQSSNQLEGQYEFMT 124
            ....|   :.:.|.|.:   .|.:.:|.:.:...|: .|.:||  :..:.||....:.|.   :|
Human    64 FDPNNSSALKIEIYPTSLTKTELENFIMQQIKRWSDLPKDTFW--LYFSQVQEIMSIFGD---IT 123

  Fly   125 HPNVKEIYENPKI-------KFDLVFLGLMANTYQLGIAAKLKCPVIISWVGIP-LPFMDTIVGN 181
            ....|::..|.|.       :||::|...:....:| :|.....|.:.|....| ..|.....|.
Human   124 RKFCKDVVSNKKFMKKVQESRFDVIFADAIFPCSEL-LAELFNIPFVYSLSFSPGYTFEKHSGGF 187

  Fly   182 VNDPSYVPTVNVALNAGQKTMD--FGLRFVNFFKYAIMCVFETVLDYKMNQFYERAFANELEFPN 244
            :..|||||.|...|......|:  ..:.:|.:|.:    .||.....|.:|||.
Human   188 IFPPSYVPVVMSELTDQMTFMERVKNMIYVLYFDF----WFEIFDMKKWDQFYS----------- 237

  Fly   245 YHEMKRRVSLLFYNYHSASEGPIR---------PTVPQSIEIGGIQVKEQADPLPKELAKFLDKA 300
              |:..|.:.|......|....||         |.:|....:||:..| .|.|||||:..|:..:
Human   238 --EVLGRPTTLSETMGKADVWLIRNSWNFQFPYPLLPNVDFVGGLHCK-PAKPLPKEMEDFVQSS 299

  Fly   301 DE-GAIFFSLGTNVNTNTFRPDTVDILYKVLSKLPQRVIWKWEDLKNKPGNAS-NIFFGNWLPQD 363
            .| |.:.||||:.|:..|  .:..:::...|:::||:|:|:::.  |||.... |.....|:||:
Human   300 GENGVVVFSLGSMVSNMT--EERANVIASALAQIPQKVLWRFDG--NKPDTLGLNTRLYKWIPQN 360

  Fly   364 DILAHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHEL 428
            |:|.||.|:.||||.|..|:.||.|||:|||.:|:|.||..|...|...|....:|..||:..:|
Human   361 DLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTMSSTDL 425

  Fly   429 EQTIREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHLQSPLIHTKFVARNN 493
            ...::.|:.:|:|:|.:.|.|.:..|:|:......::|.|:|:||:||.||:.......:...::
Human   426 LNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHS 490

  Fly   494 LDVYG--VVLLVSLLLIVTIKFLF 515
            |||.|  :|.:.:::.|||...||
Human   491 LDVIGFLLVCVATVIFIVTKCCLF 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	egt	7..475	CDD:223071	138/495 (28%)
		YjiC	27..448	CDD:224732	124/448 (28%)
UGT2B7	NP_001065.2	UDPGT	24..525	CDD:278624	147/520 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150459
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740