Protein Alignment Ugt37E1 and Ugt2a3

DIOPT Version :10

• Sequence 1: NP_652628.2
• Gene: Ugt37E1 / 53512
• FlyBaseID: FBgn0040261
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_082370.2
• Gene: Ugt2a3 / 72094
• MGIID: 1919344
• Length: 534
• Species: Mus musculus
• Alignment Length: 538
• Identity: 155/538 - (28%)
• Similarity: 258/538 - (47%)
• Gaps: 72/538 - (13%)

  Fly    37 SHVIVHMAVMKALADRGHNITV------VTQMKPKLATH-ENITVIIAPPTEERQRYIKEYMAEV 94
            ||.:....:::.|..|||.:||      :.....::..| |||.::....|.|.:      :.|:
Mouse    34 SHWLNLKTILEELGARGHEVTVLKYPSIIIDQSKRIPLHFENIPLLYEIETAENR------LNEI 92

  Fly    95 SN------EKPSFWETMVKAIVQSSNQLEGQYEFMTHPNVKEIYENPKI-------KFDLVFLGL 146
            :|      ...|.||. .|.:.....|:.|.:|.:    .:.:..|.|.       ::|:|.:..
Mouse    93 ANLAVNVIPNLSLWEA-AKTLQDFFLQVTGDFESI----CRSVLYNQKFMDKLRDAQYDVVVIDP 152

  Fly   147 MANTYQLGIAAKLKCPVIISW---VGIPLPFMDTIVGNVNDP-SYVPTVNVALNAGQKTMDFGLR 207
            :....:| :|..|:.|.:.:.   :|.   :|:...|.:..| ||||.|...|.   ..|.|..|
Mouse   153 VVPCGEL-VAEVLQIPFVYTLRFSMGY---YMEKHCGQLPIPLSYVPVVMSELT---DNMTFTER 210

  Fly   208 FVNFFKYAIMCVFETVLDYKMNQ----FYERAFANELEFP-NYHEMKRRVSLLFYNYHSASEGPI 267
            ..|.       :|..:.:|.:.|    |:::.::..|..| .:.:...:..:.....:...|.|
Mouse   211 VKNM-------MFSLLFEYWLQQYDFAFWDQFYSETLGRPTTFCKTVGKADIWLIRTYWDVEFP- 267

  Fly   268 RPTVPQSIEIGGIQVKEQADPLPKELAKFLDKADE-GAIFFSLGTNVNTNTFRPDTVDILYKVLS 331
            ||.:|....:||:..| .|.|||||:.:|:..:.| |.:.||||:.|...|  .:..:::..||:
Mouse   268 RPYLPNFEFVGGLHCK-PAKPLPKEMEEFVQSSGEHGVVVFSLGSMVKNLT--EEKANLIASVLA 329

  Fly   332 KLPQRVIWKWEDLKNKPGN-ASNIFFGNWLPQDDILAHPNTKLFITHAGKGGVAEAQYHGVPMVA 395
            ::||:|:|::..  .||.. .||....||:||:|:|.||.||.||||.|..|:.||.|||||||.
Mouse   330 QIPQKVLWRYSG--KKPATLGSNTRLFNWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVG 392

  Fly   396 LPIFGDQQGNAEIMTKSGFGRWLDILTMTEHELEQTIREVLGNPAYRETIGKFSTLYRDRPLTAR 460
            :|:.|||..|...|...|....:.|.|||..:|...:|.|:..|:|:|...:.|.::.|:|:...
Mouse   393 VPMLGDQPHNIAHMEAKGAALKVSISTMTSTDLLSAVRAVINEPSYKENAMRLSRIHHDQPVKPL 457

  Fly   461 QSVIYWTEYVLRHQGALHLQSPLIHTKFVARNNLDVYGVVLL--VSLLLIVT--IKFLFRKILNV 521
            ...::|.|:|:||:||.||:.......:...::|||.|.:||  |:|..|:|  ..|:.:|:
Mouse   458 DRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLLCVVTLTFIITKFCLFVCQKL--- 519

  Fly   522 AIGYGSQRKAVANKLKNN 539
               |..:.|.:.|:.|.|
Mouse   520 ---YMKESKKMGNRKKKN 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	GT1_Gtf-like	25..466	CDD:340817	129/459 (28%)
Ugt2a3	NP_082370.2	UDPGT	25..526	CDD:278624	151/528 (29%)