Protein Alignment Ugt37E1 and Ugt2a1

DIOPT Version :10

• Sequence 1: NP_652628.2
• Gene: Ugt37E1 / 53512
• FlyBaseID: FBgn0040261
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: XP_063129643.1
• Gene: Ugt2a1 / 63867
• RGDID: 69432
• Length: 737
• Species: Rattus norvegicus
• Alignment Length: 541
• Identity: 147/541 - (27%)
• Similarity: 243/541 - (44%)
• Gaps: 113/541 - (20%)

  Fly    37 SHVIVHMAVMKALADRGHNITVVTQMKPKLATHENITVIIAP---------PTEERQRYIKEYMA 92
            ||.:....:::.|..|.|::||       ||..|.:.:..:|         |....:..|.|.:.
  Rat   241 SHWLNIKILLEELVQRNHSVTV-------LAASETLFINSSPDAFISFEEIPVSYTRSKIDEMIE 298

  Fly    93 EV----SNEKP------SFWETMVK---AIVQSSNQL-EGQYEFMTHPNVKEIYENPKIKFDLVF 143
            .:    .:.:|      :|::.:.|   |..:.:.|: :|..:     |...:....|..||::.
  Rat   299 HMIALWLDHRPTPLTMWAFYKELGKLFAAFYKINKQICDGVLK-----NATLMARLQKGGFDVLI 358

  Fly   144 LGLMANTYQLGIAAKLKCPVIISWVGIPLPFMDTIVGNVNDP-SYVPTVNVALNAGQKTMDFGLR 207
            ...:....:| :|.||..|.:.:....|...::...|.:..| ||||   .||:.....|.||.|
  Rat   359 SDPVTMCGEL-VALKLGIPFVYTLRFSPAFTVERHCGKIPTPVSYVP---AALSELTDQMTFGER 419

  Fly   208 FVNFFKYAIMCVFETVLDY-------KMNQFYERAFAN--------------------ELEFPNY 245
            ..|...|::.       ||       :.|.:|.|....                    :.|||
  Rat   420 VKNTISYSLQ-------DYIFKSYWGEWNSYYSRVLGRPTTLCETMGKAEIWLMRTYWDFEFP-- 475

  Fly   246 HEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPKELAKFLDKADE-GAIFFSL 309
                                  ||.:|....:||:..| .|.|||||:.:|:..:.| |.:.|||
  Rat   476 ----------------------RPYLPNFEFVGGLHCK-PAKPLPKEMEEFVQTSGEHGVVVFSL 517

  Fly   310 GTNVNTNTFRPDTVDILYKVLSKLPQRVIWKWEDLKNK-PGN-ASNIFFGNWLPQDDILAHPNTK 372
            |:.|...|  .:..:::...|:::||:|:|::   |.| |.. .||....:|:||:|:|.||.|:
  Rat   518 GSMVKNLT--EEKANLIASALAQIPQKVLWRY---KGKIPATLGSNTRLFDWIPQNDLLGHPKTR 577

  Fly   373 LFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHELEQTIREVLG 437
            .||||.|..|:.||.|||:|||.:|:|.||..|...|...|....:::.|||..:|...:|.|:.
  Rat   578 AFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSADLLSAVRAVIN 642

  Fly   438 NPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHLQSPLIHTKFVARNNLDVYGVVL- 501
            .|.|:|...:.|.::.|:|:......::|.|:|:||:||.||:.......:...::|||.|.:|
  Rat   643 EPFYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLA 707

  Fly   502 -LVSLLLIVTIK---FLFRKI 518
             :.|.:|:| ||   |:|:||
  Rat   708 CMASAILLV-IKCCLFVFQKI 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	GT1_Gtf-like	25..466	CDD:340817	124/482 (26%)
Ugt2a1	XP_063129643.1	None