DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37E1 and Ugt305A1

DIOPT Version :9

Sequence 1:	NP_652628.2	Gene:	Ugt37E1 / 53512	FlyBaseID:	FBgn0040261	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001261394.1	Gene:	Ugt305A1 / 59217	FlyBaseID:	FBgn0042179	Length:	583	Species:	Drosophila melanogaster

Alignment Length:	578	Identity:	129/578 - (22%)
Similarity:	227/578 - (39%)	Gaps:	100/578 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LIAFLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALADRGHNITVV-TQMKPKLATHENIT 73
            |..|:|.....|...||||.:..|...::......:..||...||::.|: |...|:.....:..
  Fly     7 LPVFVLLGRFCSLEAANILCLVSTAKHNNPGWSKPLFDALLANGHSLLVISTAPNPEPKKQVDGL 71

  Fly    74 VIIAPPTE---ERQRYI----KEYMAEVSNEKPSFW--------------ETMVKAIVQSSNQLE 117
            |....|.|   .::.::    :||::.|:..:...|              :||.....:.:.||.
  Fly    72 VYYHLPNEYDVMKRHFLLEEPREYISMVTLNQLLVWYEVLLGSCRALLNSDTMSSKRPELTAQLS 136

  Fly   118 GQYEFMTHPNVKEIYENPKIKFDLVFLGLMANTYQLGIAAKLKCPVIISWVGIPLPFMDTIVGNV 182
            .:|:.:    :.::.:..:...|.| .|..:... ||::|....|.::|     |...:..:...
  Fly   137 MEYDLI----ITDVTQGIECLMDSV-SGWRSKPV-LGLSAGKLTPDLMS-----LLRAENTINAA 190

  Fly   183 NDPSYVPTVNVALNAGQKTMDFGLRFVNFFKYAI-----MCVFETVLDYKMNQFYERAFANELEF 242
            ..|.|:..|       .|||.|..|..|...|..     :.:...||...|.        .|..|
  Fly   191 RIPHYISQV-------PKTMGFWNRLHNHIMYYAEPLIHLVITRPVLSELMK--------TENAF 240

  Fly   243 PNYHEMKRRVSLLFYNYHSASEGPIRPTV-------PQSIEIGGIQVKEQADPLPKELAKFLDKA 300
            |       ::.|:..|.|        ||:       |..||:||:.:|.|..|||..:.:|.:|.
  Fly   241 P-------KLQLVLLNTH--------PTLDYVQNLPPGVIEVGGLHIKNQTSPLPTYIQEFTEKF 290

  Fly   301 DEGAIFFSLGTNVNTNTFRPDTVDILYKVLSKLPQ-RVIWKWEDLKNKPGNASNI--FFGNWLPQ 362
            .:|.::.::......|   ...:..:|.::...|. ..||..|.|:..|....|:  ...|...|
  Fly   291 FDGIVYINMPYIEYMN---DQGLKAMYTMIHGNPNVAFIWNVEQLEQLPAKKPNLLTLHVNQSLQ 352

  Fly   363 DDILAHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHE 427
            .||||....|.|:.|.....:.||.::|||:|.||:..::..||:.:.:...|..|.:....:..
  Fly   353 QDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQRVMERNLGVMLQVKEFNQSS 417

  Fly   428 LEQTIREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVL------RHQGALHLQSPLIHT 486
            |...:..:|....:...:.:....:|.||.:|.:..::..|.::      :|    ..|:..:..
  Fly   418 LSDALTRILDEERFISALHQAQLKFRTRPQSALELAVWHAEQLIAEPRLFKH----FAQTETLAQ 478

  Fly   487 KFVARNNLDVYGVVLLVSLLLIVTIKFLFRKILNVAIGYGSQR-----KAVANKLKNN 539
            .|...|:|||..|.|:|.|..:|::    ..::.|....||:|     |||..|.|.:
  Fly   479 NFFVANSLDVLTVPLIVLLAAVVSL----ANLVYVLYTGGSKRQQTLEKAVLKKRKKS 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	egt	7..475	CDD:223071	109/507 (21%)
Ugt37E1	NP_652628.2	YjiC	27..448	CDD:224732	97/457 (21%)
Ugt305A1	NP_001261394.1	Glycosyltransferase_GTB_type	<242..461	CDD:299143	55/229 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445824
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.950