Protein Alignment Ugt37E1 and Ugt2a2

DIOPT Version :10

• Sequence 1: NP_652628.2
• Gene: Ugt37E1 / 53512
• FlyBaseID: FBgn0040261
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001019319.1
• Gene: Ugt2a2 / 552899
• MGIID: 3576095
• Length: 528
• Species: Mus musculus
• Alignment Length: 564
• Identity: 149/564 - (26%)
• Similarity: 259/564 - (45%)
• Gaps: 100/564 - (17%)

  Fly     6 KIGFLIAFLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALADRGHNITVVTQ-----MKPK 65
            |:..|:.|.| |:.:.....|:: |:.|.. ||.:....:::.|..|.|::||:..     :..:
Mouse     4 KVLQLLIFHL-TLAEIVLSGNVV-VWPTDG-SHWLNIKILLEELVQRNHSVTVLAPSETLFINSR 65

  Fly    66 LATHENITVIIAPPTEERQRYIKEYM------------------AEVSNEKPSFWETMVKAIVQS 112
            |....|...|....|:.:...|.|:|                  .|:.|...:|:.|       :
Mouse    66 LDAFINFEEIPVSYTKSKIDEIIEHMIALWLDHRPTPLTMWTFYKELGNLLATFYTT-------N 123

  Fly   113 SNQLEGQYEFMTHPNVKEIYENPKIKFDLVFLGLMANTYQLGIAAKLKCPVIISWVGIPLPFMDT 177
            ....:|   .:.:|.|.|..:  |..||::....:....:| :|.||..|.:.:....|...::.
Mouse   124 KQMCDG---VLNNPTVMERLQ--KGGFDVLLADPVTMCGEL-VALKLGIPFVYTLRFSPAFTVER 182

  Fly   178 IVGNVNDP-SYVPTVNVALNAGQKTMDFGLRFVNFFKYAIM-CVFETVLDYKMNQFYERAFAN-- 238
            ..|.:..| ||||   .||:.....|.||.|..|...|::. .:|:|... :.|.:|.:....
Mouse   183 HCGKIPAPISYVP---AALSELTDQMSFGERVKNIISYSLQDYIFKTYWG-EWNSYYSKVLGRPT 243

  Fly   239 ------------------ELEFPNYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQ 285
                              :.|||                        ||.:|....:||:..| .
Mouse   244 TLCETMGKAEIWLMRTYWDFEFP------------------------RPYLPNFEFVGGLHCK-P 283

  Fly   286 ADPLPKELAKFLDKADE-GAIFFSLGTNVNTNTFRPDTVDILYKVLSKLPQRVIWKWE-DLKNKP 348
            |.|||||:.:|:..:.| |.:.||||:.|...|  .:..:::...|:::||:|:|::: .:.:..
Mouse   284 AKPLPKEMEEFVQTSGEHGIVVFSLGSMVKNLT--DEKANLIASALAQIPQKVLWRYKGKIPDTL 346

  Fly   349 GNASNIFFGNWLPQDDILAHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSG 413
            |:.:.:|  :|:||:|:|.||.|:.||||.|..|:.||.|||:|||.:|:|.||..|...|...|
Mouse   347 GSNTRLF--DWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKG 409

  Fly   414 FGRWLDILTMTEHELEQTIREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALH 478
            ....:::.|||..:|...:|.|:..|:|:|...:.|.::.|:|:......::|.|:|:||:||.|
Mouse   410 AAVEVNMNTMTSSDLLNALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKH 474

  Fly   479 LQSPLIHTKFVARNNLDVYGVVL--LVSLLLIVT--IKFLFRKI 518
            |:.......:...::|||.|.:|  :.|.:|:|.  ..|:|:|:
Mouse   475 LRVAAHDLSWFQYHSLDVIGFLLACVASAILLVAKCCLFIFQKV 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	GT1_Gtf-like	25..466	CDD:340817	124/487 (25%)
Ugt2a2	NP_001019319.1	UDPGT	22..516	CDD:278624	142/541 (26%)