DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37E1 and Ugt37C1

DIOPT Version :9

Sequence 1:	NP_652628.2	Gene:	Ugt37E1 / 53512	FlyBaseID:	FBgn0040261	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	500	Identity:	235/500 - (47%)
Similarity:	323/500 - (64%)	Gaps:	21/500 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 MAVMKALADRGHNITVVTQMKPKLATHENITVIIAPPTEERQRYIKEYMAEVSNEKPSFWETMVK 107
            |:..||||:.|||:|||:.|:||: .|::|.:|:.|.|:|::|.::..||.::..|.:...||..
  Fly     1 MSTAKALAEAGHNVTVVSMMQPKV-MHKDIHLIVVPVTKEQERTLENQMASMAGSKNNIITTMYL 64

  Fly   108 AIVQSSNQLEGQYEFMTHPNVKEIYENPKIKFDLVFLGLMANTYQLGIAAKLKCPVIISWVGIPL 172
            .:......:..|.:.:..|..:.::|.   ||||:.||...|.:|||:|.|||.|||:.|: ||.
  Fly    65 LLNGLDVMVTSQADLLKDPRFQRVFET---KFDLMILGSFFNDFQLGVAGKLKVPVIVDWM-IPS 125

  Fly   173 PFM-DTIVGNVNDPSYVPTVNVALNAGQKTMDFGLRFVNFFKYAIMCVFETVLDYKMNQFYERAF 236
            ..| |..|.|.::.||||..:.....   .|.|..|..|..|:.|:.......:||.|:.|...|
  Fly   126 NTMIDEFVANPSEVSYVPNESTFATT---PMSFFKRAENLVKHVILKYLTIRFNYKFNRIYNEIF 187

  Fly   237 ANELEFPNYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPKELAKFLDKAD 301
            .:: :.|...|||:.:|::|...|..|:|||||.||..||:||||||||.||||:::.:|::.:.
  Fly   188 TDK-DMPTLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKEQPDPLPQDIEQFMENSS 251

  Fly   302 EGAIFFSLGTNVNTNTFRPDTVDILYKVLSKLPQRVIWKWEDLKNKPGNASNIFFGNWLPQDDIL 366
            :||||.|.|:|:.:...:|:.|.|::||||.|.|.||||||||:|.||||||||:.:||||||||
  Fly   252 QGAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWEDLENTPGNASNIFYKDWLPQDDIL 316

  Fly   367 AHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHELEQT 431
            ||||||||:||||||.:.|:|||||||||||||||...||.:|..||:|..||:.|:||....:.
  Fly   317 AHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQTITEDTFREA 381

  Fly   432 IREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHLQSPLIHTKFVARNNLDV 496
            |.|||.|..|.:.:.|||.||||||||.||||::|.:|||||.||.:||||.:|..||..:|||:
  Fly   382 INEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVHMGFVELHNLDI 446

  Fly   497 YGVVLLVSLLLI----VTIKFLFRKILNVAIGYGSQRKAVANKLK 537
            |.:||.:.:.|:    :|:||||.|:|..|       |..|.|.|
  Fly   447 YALVLAILIFLVFLTRLTVKFLFSKLLGKA-------KVPARKKK 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	egt	7..475	CDD:223071	207/432 (48%)
Ugt37E1	NP_652628.2	YjiC	27..448	CDD:224732	186/405 (46%)
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	231/491 (47%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	210/435 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445648
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H86211
Inparanoid	1	1.050	83	1.000	Inparanoid score	I2351
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D51205at7147
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm50532
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	10	10.000