DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37E1 and Ugt302C1

DIOPT Version :9

Sequence 1:	NP_652628.2	Gene:	Ugt37E1 / 53512	FlyBaseID:	FBgn0040261	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster

Alignment Length:	555	Identity:	160/555 - (28%)
Similarity:	267/555 - (48%)	Gaps:	58/555 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GFLIAFLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALADRGHNITVVTQMKPKLATHENI 72
            ||| |.||..:.......|.|.|..|.:.||..|..|:.|.||..||.:|:::..:.|... :||
  Fly     9 GFL-ALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPI-KNI 71

  Fly    73 TVIIAPPTEERQRYIKEYMAEVSNEKPSFWETMVKAIVQSSNQ-LEGQYEFMTHPNVKEIYENPK 136
            ..:.|      :..:......::|...|..|.::|.|:..... :|.....:..|:|.|:.::.:
  Fly    72 KDVPA------KSILTSMQGRIANLLQSSKEPIIKQIINFHEMGIEITELLLKEPSVIELMKSNQ 130

  Fly   137 IKFDLVFLGLMANTYQLGIAAKLKCPVI-------ISWVGIPLPFMDTIVGNVNDPSYVPTVNVA 194
             .||.|...:..|....|.|...|.|:|       |||       ...:||:.:.|||||:..:.
  Fly   131 -TFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISW-------NTDLVGSPSPPSYVPSALLK 187

  Fly   195 LN---------AGQKTMDFGLRFVNFFKYAIMCVFETVLDYKMNQ--FYERAFANELEFPNYHEM 248
            .:         ..|..:.:...|:|:|             |...|  .|.:.|.|..:  ::::|
  Fly   188 FSDRMSLVERVGNQAFLTYEYIFLNYF-------------YLPRQEVLYRKYFPNNKQ--DFYDM 237

  Fly   249 KRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPKELAKFLDKADEGAIFFSLGTNV 313
            ::..:|:..|.|.:...| ||..|..||:||:.:..:..||||::.:|::.|:.|.|:||:|:|:
  Fly   238 RKNTALVLLNQHVSLSFP-RPYSPNMIEVGGMHINRKRQPLPKDILEFIEGAEHGVIYFSMGSNL 301

  Fly   314 NTNTFRPDTVDILYKVLSKLPQRVIWKWEDLKNKPGNASNIFFGNWLPQDDILAHPNTKLFITHA 378
            .:.|...:....|....::|.|||:||:|| .:.||..:|:|..:|.||||||||.|...||||.
  Fly   302 KSKTLPLEKRQALIDTFAQLKQRVLWKFED-TDLPGKPANVFISDWFPQDDILAHDNVLAFITHG 365

  Fly   379 GKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHELEQTIREVLGNPAYRE 443
            |.....|:.||..|.|.:||||||..|.....::|:|..:....::..:|...|::::.||...:
  Fly   366 GLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQ 430

  Fly   444 TIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHLQSPLIHTKFVARNNLD----VYGVVLLVS 504
            .:...|..|||:..|..:..:||.|:|.||:||.:|:|......|:..:|||    :||.::.|.
  Fly   431 RVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVL 495

  Fly   505 LLLIVTIKFLFRKILNVAIGYGSQRKAVANKLKNN 539
            ..:.:.|:.::|.:..:.|...:.:.  ..|.|.|
  Fly   496 YCIFLLIRLVWRLLQELFIKKDTSKP--KQKAKRN 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	egt	7..475	CDD:223071	143/485 (29%)
Ugt37E1	NP_652628.2	YjiC	27..448	CDD:224732	125/439 (28%)
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	115/373 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445759
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.850