Protein Alignment Ugt37E1 and ugt5a3

DIOPT Version :10

• Sequence 1: NP_652628.2
• Gene: Ugt37E1 / 53512
• FlyBaseID: FBgn0040261
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001170962.3
• Gene: ugt5a3 / 322378
• ZFINID: ZDB-GENE-030131-1097
• Length: 524
• Species: Danio rerio
• Alignment Length: 567
• Identity: 157/567 - (27%)
• Similarity: 260/567 - (45%)
• Gaps: 106/567 - (18%)

  Fly     5 TKIGFLIAFLLSTMTQS-SGGANILGVFGTHSPSHVIVHMAVM-KALADRGHNITVVT-----QM 62
            |.:|..:  ||..:::| :|...::.|.|:|     .|:|.|: ..|..|||:||||.     .:
Zfish     5 THLGLFL--LLCALSRSYAGKLLVVPVDGSH-----WVNMKVLIVELHSRGHSITVVRGSSSWYI 62

  Fly    63 KPKLATHENITVIIAPPTEERQRYIKEYMAEVSNEKPSFWETMVKAIVQSSNQLEGQYEF--MTH 125
            :.:...:.:|||......::.......::.::..:..|||..|..|....|...|...|.  ||
Zfish    63 EEQSPLYTSITVDNGVFDDDFMETFLPHLLKMQRQGKSFWNEMALADETYSRFTEIHQEICKMT- 126

  Fly   126 PNVKEIYENPKI-------KFDLV-----FLGLMANTYQLGIAAKLKCPVI--ISWVGIPLPFMD 176
               ..::||..:       .:|:|     |.|.:...::||:      |::  :.|
Zfish   127 ---ATMFENETLMNSLKDAAYDVVLTDPAFGGGVLLAHRLGL------PLVYNVRW--------- 173

  Fly   177 TIVGNVN-----DP-SYVPTVNVALNAGQKTMDFGLRFVNFFKYAIMCVFETVLDYKMNQFY--- 232
            |:.|..:     .| ||||...:.|.   ..|.|..|.:|...|.::.       ||.::::
Zfish   174 TMYGEAHFDIAPTPLSYVPVTGLQLT---DKMTFSQRVMNMMTYIMIL-------YKNSKYFGSP 228

  Fly   233 -----ERAFANELEFPNYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPKE 292
                 ::.|...:   |:..:.:...|.........|.| |||:|..:.:||.|.| .|.|||.:
Zfish   229 YQELTQKYFGPNV---NFFSLLQDADLWLMRNDFTFEFP-RPTMPNVVYMGGFQCK-PAKPLPGD 288

  Fly   293 LAKFLDKADE-GAIFFSLGT-------NVNTNTFRPDTVDILYKVLSKLPQRVIWKWEDLKNKPG 349
            |.:|:..:.| |.|..||||       .:|         |.:....::|||:|||::..  .:|.
Zfish   289 LEEFVQSSGEHGVIMMSLGTVFGQLLSELN---------DEIAAAFAQLPQKVIWRYTG--PRPA 342

  Fly   350 N-ASNIFFGNWLPQDDILAHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSG 413
            | .:|....|||||:|:|.||.||||:.|.|..|:.||.|||||:|.||:..||..|...|...|
Zfish   343 NLGNNTLIVNWLPQNDLLGHPKTKLFVAHGGTNGLQEAIYHGVPIVGLPLAFDQPDNLSRMRAKG 407

  Fly   414 FGRWLDILTMTEHELEQTIREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALH 478
            ..:.:||.|:......:.::|||.|.:|||.:.:.|.|:.|:|:......|:|.|:|:|::||.|
Zfish   408 TAKIVDIATLDRAVFLEALKEVLHNASYRENMQRLSKLHHDQPMKPLDRAIFWIEFVMRNKGAPH 472

  Fly   479 LQSPLIHTKFVARNNLDVYGVVLLVSLLLIVTIKF--------LFRK 517
            |::......::...::||...::|:.|:..:...:        ||||
Zfish   473 LRTQSFRMSWIEYQSIDVILTLMLMVLVFALVTAYMTKYFCLCLFRK 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	GT1_Gtf-like	25..466	CDD:340817	135/485 (28%)
ugt5a3	NP_001170962.3	None