Protein Alignment Ugt37E1 and Ugt1a1

DIOPT Version :10

• Sequence 1: NP_652628.2
• Gene: Ugt37E1 / 53512
• FlyBaseID: FBgn0040261
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_036815.1
• Gene: Ugt1a1 / 24861
• RGDID: 3935
• Length: 535
• Species: Rattus norvegicus
• Alignment Length: 556
• Identity: 148/556 - (26%)
• Similarity: 253/556 - (45%)
• Gaps: 79/556 - (14%)

  Fly    10 LIAFLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALADRGHNITVVTQMKPKLATHENITV 74
            |:..:|......:|...::.:.|    ||.:..:.|::.|..:||.:.|:.   |:.:.|
  Rat    17 LLLCVLGPSASHAGKLLVIPIDG----SHWLSMLGVIQQLQQKGHEVVVIA---PEASIH----- 69

  Fly    75 IIAPPTEERQRY-IKEYMAEVSNEKPSFWETMVKAIVQSSNQLEGQYEFMTHPNVKEIYENPKIK 138
                 .:|...| :::|.....|      |.:..|.|:....:..|..|:.  .|.:.|...|..
  Rat    70 -----IKEGSFYTMRKYPVPFQN------ENVTAAFVELGRSVFDQDPFLL--RVVKTYNKVKRD 121

  Fly   139 FDLVFLG---------LMANTYQLGIAAKLKCP------VIISWVGIPLPF--------MDTIVG 180
            ..::..|         .||:..|....|.|..|      ::..::.:|..:        :|....
  Rat   122 SSMLLSGCSHLLHNAEFMASLEQSHFDALLTDPFLPCGSIVAQYLSLPAVYFLNALPCSLDLEAT 186

  Fly   181 NVNDP-SYVPTVNVALNAGQKTMDFGLRFVNFFKYAIMCVFETVLDYKMNQFYERAFANEL--EF 242
            ....| ||||.   :|::....|:|..|..|.    |:.:.|..|...:...| .:.|.|:  :.
  Rat   187 QCPAPLSYVPK---SLSSNTDRMNFLQRVKNM----IIALTENFLCRVVYSPY-GSLATEILQKE 243

  Fly   243 PNYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPKELAKFLDKADE-GAIF 306
            ....::....|:.........:.| ||.:|..:.||||... |...|.:|...:::.:.| |.:.
  Rat   244 VTVKDLLSPASIWLMRNDFVKDYP-RPIMPNMVFIGGINCL-QKKALSQEFEAYVNASGEHGIVV 306

  Fly   307 FSLGTNVNTNTFRPDTVDI-LYKVLSKLPQRVIWKWEDLKNKPGN-ASNIFFGNWLPQDDILAHP 369
            ||||:.|:.   .|:...: :.:.|.::||.|:|::..  .:|.| |.|.....||||:|:|.||
  Rat   307 FSLGSMVSE---IPEKKAMEIAEALGRIPQTVLWRYTG--TRPSNLAKNTILVKWLPQNDLLGHP 366

  Fly   370 NTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHELEQTIRE 434
            ..:.||||:|..|:.|...:|||||.:|:||||..||:.|...|.|..|::|.||..:||..::.
  Rat   367 KARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKT 431

  Fly   435 VLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHLQSPLIHTKFVARNNLDVYGV 499
            |:.|.:|:|.|.:.|:|::|||:......::|.|||:||:||.||:.......:...::|||.|.
  Rat   432 VINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGF 496

  Fly   500 VLLVSLLLIVTIKFLFRKILNVAIGYGSQRKAVANK 535
            :|.:    ::|:.|:..|    :..||. ||....|
  Rat   497 LLAI----VLTVVFIVYK----SCAYGC-RKCFGGK 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	GT1_Gtf-like	25..466	CDD:340817	122/470 (26%)
Ugt1a1	NP_036815.1	UDPGT	30..526	CDD:278624	146/543 (27%)