Protein Alignment Ugt37E1 and Ugt2b35

DIOPT Version :10

• Sequence 1: NP_652628.2
• Gene: Ugt37E1 / 53512
• FlyBaseID: FBgn0040261
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_766469.1
• Gene: Ugt2b35 / 243085
• MGIID: 3576100
• Length: 529
• Species: Mus musculus
• Alignment Length: 520
• Identity: 147/520 - (28%)
• Similarity: 242/520 - (46%)
• Gaps: 108/520 - (20%)

  Fly    37 SHVIVHMAVMKALADRGHNITVVTQMKPKLATHENITVIIAP-----------PTEERQRYIKEY 90
            ||.:....::..|..|||.:||   ::|      :.::.:.|           ||...:.|::.:
Mouse    34 SHWMNLKIILDELVQRGHEVTV---LRP------SASIFVDPKYSPGLKFETFPTAFSKDYLETF 89

  Fly    91 MAEVSNEKPSFWETMVK-------AIVQSSNQLEGQYEFMTHPNVKEIYENPKI-------KFDL 141
            :.::.:|    |...|.       :::|:   |.|:....:....||...|.::       |||:
Mouse    90 LTKLVDE----WTFEVPRDTCLSYSLLQT---LFGKLSDYSLSLCKEAVSNKQLMTKFQESKFDV 147

  Fly   142 VFLGLMANTYQLGIAAKLKCPVIISWVGIPLPFMDTIVGN-VNDPSYVPTVNVALNAGQKTMDFG 205
            :.|..||:..:| ||..|:.|.:.|....|...::...|. |..|||||.:...| .||  |.|.
Mouse   148 LILDAMASCGEL-IAQLLQIPFLYSLRFSPGYQVEKNSGGFVLPPSYVPVILSGL-GGQ--MTFT 208

  Fly   206 LRFVNFFKYAIMCV------FETVLDYKMNQFYERAFAN--------------------ELEFPN 244
            .|..|     ::|:      |:|..:.:.:|||......                    :||||:
Mouse   209 ERVKN-----MICMLYFDFWFQTFTEKEWDQFYSETLGRPTTLIETMGKAEMWFIRSYWDLEFPH 268

  Fly   245 YHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPKELAKFLDKAD-EGAIFFS 308
                                    ||:|....:||:..| .|.|||||:..|:..:. .|.:.||
Mouse   269 ------------------------PTLPNVEYVGGLHCK-PAKPLPKEMEDFVQSSGVHGVVVFS 308

  Fly   309 LGTNVNTNTFRPDTVDILYKVLSKLPQRVIWKWEDLKNKPGNASNIFFGNWLPQDDILAHPNTKL 373
            ||:.|:..|  .:..:.:...|:::||:|:|:: |.|.......|.....||||:|:|.||.||.
Mouse   309 LGSMVSNMT--EERANAISWALAQIPQKVLWRF-DGKTPASLGPNTRIYKWLPQNDLLGHPKTKA 370

  Fly   374 FITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHELEQTIREVLGN 438
            |:||.|..|:.||.:||:||:.:|:|.:|..|...|...|....|:|.||:..:|...:.||:.|
Mouse   371 FVTHGGANGLYEAIHHGIPMIGIPLFSEQHDNIAHMVAKGTAVALNIRTMSRSDLLNALEEVINN 435

  Fly   439 PAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHLQSPLIHT-KFVARNNLDVYGVVLL 502
            |:|:|.:...||::.|:|:......|:|.|:|:||:||.||: ||.|. .:...::|||.|.:|:
Mouse   436 PSYKENVMWLSTIHHDQPMKPLNRTIFWIEFVMRHKGAKHLR-PLAHNLTWYQYHSLDVIGFLLV 499

  Fly   503  502
            Mouse   500  499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	GT1_Gtf-like	25..466	CDD:340817	130/481 (27%)
Ugt2b35	NP_766469.1	UDPGT	24..525	CDD:278624	147/520 (28%)