Protein Alignment Ugt37E1 and Ugt2b5

DIOPT Version :10

• Sequence 1: NP_652628.2
• Gene: Ugt37E1 / 53512
• FlyBaseID: FBgn0040261
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_033493.3
• Gene: Ugt2b5 / 22238
• MGIID: 98900
• Length: 530
• Species: Mus musculus
• Alignment Length: 553
• Identity: 150/553 - (27%)
• Similarity: 251/553 - (45%)
• Gaps: 108/553 - (19%)

  Fly    37 SHVIVHMAVMKALADRGHNITVVTQ-----MKPKLATHENITVIIAPPT----EERQRYIKEYMA 92
            ||.:....::..|..|||.:||:..     :.||.:........   ||    :..:.:..:::.
Mouse    34 SHWMNIKIILDELVQRGHEVTVLRPSAYYVLDPKKSPGLKFETF---PTSVSKDNLENFFIKFVD 95

  Fly    93 EVSNEKPSFWETMVKAIVQSSNQLEGQYEFMTH--PNVKEIYENPKI-------KFDLVFLGLMA 148
            ..:.|.|.  :|.:.......|.::   ||..:  ...|::..|.::       |||::....:|
Mouse    96 VWTYEMPR--DTCLSYSPLLQNMID---EFSDYFLSLCKDVVSNKELMTKLQESKFDVLLSDPVA 155

  Fly   149 NTYQLGIAAKLKCPVIISWVGIPLPFMDTIVGN-VNDPSYVPTVNVALNAGQKTMDFGLRFVNFF 212
            :..:| ||..|:.|.:.|....|...::...|. :..|||||.:...| .||.|      |:...
Mouse   156 SCGEL-IAELLQIPFLYSIRFSPGYQIEKSSGRFLLPPSYVPVILSGL-GGQMT------FIERI 212

  Fly   213 KYAIMCV------FETVLDYKMNQFYERAFAN--------------------ELEFPNYHEMKRR 251
            |..| |:      |:...|.|.:.||......                    :||||:
Mouse   213 KNMI-CMLYFDFWFQMFNDKKWDSFYSEYLGRPTTLVETMGQAEMWLIRSNWDLEFPH------- 269

  Fly   252 VSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPKELAKFLDKA-DEGAIFFSLGTNVNT 315
                             ||:|....:||:..| .|.||||::.:|:..: |.|.:.||||:.|:.
Mouse   270 -----------------PTLPNVDYVGGLHCK-PAKPLPKDMEEFVQSSGDHGVVVFSLGSMVSN 316

  Fly   316 NTFRPDTVDILYKVLSKLPQRVIWKWEDLKNKPGNASNIFFGNWLPQDDILAHPNTKLFITHAGK 380
            .|  .:..:.:...|:::||:|:||: |.|.......|.....||||:|:|.||.||.|:||.|.
Mouse   317 MT--EEKANAIAWALAQIPQKVLWKF-DGKTPATLGHNTRVYKWLPQNDLLGHPKTKAFVTHGGA 378

  Fly   381 GGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHELEQTIREVLGNPAYRETI 445
            .||.||.|||:||:.:|:||:|..|...|...|....|:|.||::.::...:.||:.||.|::..
Mouse   379 NGVYEAIYHGIPMIGIPLFGEQHDNIAHMVAKGAAVALNIRTMSKSDVLNALEEVIENPFYKKNA 443

  Fly   446 GKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHLQSPLIHT-KFVARNNLDVYGVVL-LVSLLLI 508
            ...||::.|:|:......::|.|:|:||:.|.||: ||.|. .:...::|||.|.:| .|:..::
Mouse   444 MWLSTIHHDQPMKPLDRAVFWIEFVMRHKRAKHLR-PLGHNLTWYQYHSLDVIGFLLSCVATTIV 507

  Fly   509 VTIK---FLFRKILNVAIGYGSQRKAVANKLKN 538
            :::|   |::|..:.           ..||:||
Mouse   508 LSVKCLLFIYRFFVK-----------KENKMKN 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	GT1_Gtf-like	25..466	CDD:340817	126/474 (27%)
Ugt2b5	NP_033493.3	UDPGT	24..527	CDD:278624	147/549 (27%)