DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37E1 and ugt-56

DIOPT Version :9

Sequence 1:	NP_652628.2	Gene:	Ugt37E1 / 53512	FlyBaseID:	FBgn0040261	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_506074.2	Gene:	ugt-56 / 188073	WormBaseID:	WBGene00011453	Length:	524	Species:	Caenorhabditis elegans

Alignment Length:	546	Identity:	136/546 - (24%)
Similarity:	227/546 - (41%)	Gaps:	141/546 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 SHVIVHMAVMKALADRGHNITVVT-----QMKPKLAT--HENITVIIAP-----------PT--- 80
            |||.....:...||.|||.:||:.     .:..:|::  ||.|:|..:|           ||
Worm    31 SHVYFTARIANVLAARGHKVTVIDNVFRYDVDNELSSDIHEIISVEPSPEVTKLLNTGSLPTILW 95

  Fly    81 -----EERQRYIKEYMAEVSNEKPSFWETMVKAIVQSSNQL----EGQYEFMTHPNVKEIYENPK 136
                 .|.||.|.|.:..|.       ......::::|..:    |.:::|..|    |:
Worm    96 NSKASPEEQRTIMEGLGHVH-------RLQCTHLIENSTLIPKLQEIKFDFAIH----EV----- 144

  Fly   137 IKFDLVFLGLMANTYQLGIAAKLKCPVIISWVGIPLPFMDTIVGNVNDPSYVPTVNVALNAGQKT 201
              ||...:|::.   .:|:    :..||:|..| |:..:...:|          ::..||.....
Worm   145 --FDSCGVGILE---VIGV----QKTVIVSSTG-PMDVVPITLG----------ISDTLNTPSLL 189

  Fly   202 MDFGLRFVNFFK-------YAIMCVFETVLDYKMNQFYERAFANELEFPNYHEMKRRVSLLFYNY 259
            .|:| .:::||:       .:.|..|..:.|..::..:::.:.  |:.|. .|:.|:.:|||||.
Worm   190 SDYG-SYLSFFEKRRNLKFLSGMLNFHEMQDSMISPLFKKYYG--LKKPT-GEIMRQANLLFYNI 250

  Fly   260 HSASEGPIRPTVPQSIEIGGIQVKEQ-----------ADPLPKELAKFLDKADEGAIFFSLGTNV 313
            |..|:| :|....:|.:||||..|:|           :||.||.|..|             || .
Worm   251 HEGSDG-MRMRGRRSFDIGGIAFKDQKNLTMEYQTLLSDPRPKVLVSF-------------GT-A 300

  Fly   314 NTNTFRPDTVDILYKVLSKLPQRV--IWKWE---DLKNKPGNASNIFFGNWLPQDDILAHPNTKL 373
            .|::..|..:........|....|  |||:|   :...:....:||.|..:|||.|:||.....|
Worm   301 ATSSHMPQNLKNSLMTAMKQMNNVLFIWKYEMEDNFTKQEELTTNIIFKKFLPQTDLLASSKIDL 365

  Fly   374 FITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHELEQTIREVL-- 436
            |:||.|:..:.||...||.::|:|:||||..||::..::|.   ::||..::.|....|.:.:
Worm   366 FVTHCGQNSLLEAFNSGVRVLAVPLFGDQHRNAKLAFENGL---IEILPKSDIETPAKIVKAVKT 427

  Fly   437 ---GNPAYRETIGKFSTLYRDRPLTARQSVI------YWTEYVLRHQGALHLQSPLIHTKFVAR- 491
               .|....:.|...|:|.|:....|...:|      |.||:            |...:||...
Worm   428 GLEPNAKLDQNIVLISSLLRNSKENAENLLISTIEATYSTEF------------PPNFSKFPKNY 480

  Fly   492 --NNLDVYGVVLLVSLLLIVTIKFLF 515
              |.|    |.|:.|.:.:|.:.|:|
Worm   481 HPNTL----VRLIDSSIALVFMLFIF 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	egt	7..475	CDD:223071	125/501 (25%)
Ugt37E1	NP_652628.2	YjiC	27..448	CDD:224732	117/468 (25%)
ugt-56	NP_506074.2	Glycosyltransferase_GTB_type	<216..>399	CDD:299143	62/200 (31%)
ugt-56	NP_506074.2	Glycosyltransferase_GTB_type	<353..453	CDD:299143	32/102 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910