DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37E1 and ugt-30

DIOPT Version :9

Sequence 1:	NP_652628.2	Gene:	Ugt37E1 / 53512	FlyBaseID:	FBgn0040261	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_506729.1	Gene:	ugt-30 / 187955	WormBaseID:	WBGene00011340	Length:	535	Species:	Caenorhabditis elegans

Alignment Length:	562	Identity:	137/562 - (24%)
Similarity:	239/562 - (42%)	Gaps:	71/562 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FLIAFLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALAD----RGHNIT----VVTQMKPK 65
            :|.:.:...:...|...|||    .::|:....|...:..|||    ||||:|    ||...|..
Worm     3 YLQSIIFFCLLLYSNCLNIL----VYAPAFAASHSKFLGKLADTLTERGHNVTYLMPVVNIAKRD 63

  Fly    66 LATHENIT--VIIAPPTEERQRYIKEYMAEVSNEK-PSFWETMVKAIVQSSNQLEGQYEFMTHPN 127
            ......||  |:|   .|..::.:.:..|:..|:: ...|.|:.   :.|||..|....|.:...
Worm    64 ECKGVKITKDVVI---VEAGEKMLSQKQADTPNDEILDVWWTVQ---MDSSNSREIFQFFCSDMK 122

  Fly   128 V--------KEIYENPKIK-FDLVFL------GLMANTYQLGI------AAKLKCPVIISWVGIP 171
            :        ::|:|:.|.: |||..|      || .....|||      ::.:...||:.::|.|
Worm   123 IACENFLSRRDIFEDMKARNFDLAILEPVSACGL-GFVKALGIEKTILASSSVFYDVILPYIGEP 186

  Fly   172 LPFMDTIVGNVNDPSYVPTVNVALNAGQKTMDFGLRFVNFF-KYAIMCVFETVLDYKMNQFYERA 235
            |           |.||||:   ..:...:.:..|.:|.|:. ...|....|.:.|.:| :.|.|.
Worm   187 L-----------DYSYVPS---GYSVTGQELSLGEKFENWMVSREISIALEGLFDGEM-EIYRRL 236

  Fly   236 FANELEFPNYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVK---EQADPLPKELAKFL 297
            ..:.|  .|:..:....|:.|.|.:...:.| ||.:.:::.||||.|.   .:.|.|.:|..|.|
Worm   237 LGHNL--TNWRHLFPSASIFFVNSNPFFDFP-RPVLEKTVPIGGISVNMGVRKEDMLTEEWEKVL 298

  Fly   298 DKADEGAIFFSLGTNVNTNTFRPDTVDILYKVLSKLPQ-RVIWKWEDLKNKPGNA-SNIFFGNWL 360
            ::... .:..|.||.|.:..........|.:.....|. ..|||:|...:...|. .||:|..|:
Worm   299 NQRPH-TMLVSFGTLVMSTHMPKKWRSGLLEAFKSFPNVTFIWKYESDDHSFANGIDNIYFSKWV 362

  Fly   361 PQDDILAHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTE 425
            ||:::|.......|::|.|.|.:.|..:.|.|.:.:|:|.||..||..:.:......|....|..
Worm   363 PQNELLNDNRLTAFLSHGGLGSIMELAFSGKPALIIPVFADQTRNANTLARHRGAICLHKSQMKN 427

  Fly   426 HE-LEQTIREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHLQSPL-IHTKF 488
            .| |::..:.||.:.:::....|.:...|::|...:.::|.:||:| ...|......|. .|...
Worm   428 TEVLKKAFKSVLFDASFKNNSLKLAATLRNQPNKPKDTLIKYTEFV-GEFGPFPQMDPYGRHLNV 491

  Fly   489 VARNNLDVYGVVLLVSLLLIVTIKFLFRKILNVAIGYGSQRK 530
            ..::.:|:|.::::||.:.:..|..:..|::...|...|..|
Worm   492 FQKSFIDIYTLIIVVSSIFVALIFNVIAKLIQYFIKSKSSEK 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	egt	7..475	CDD:223071	125/504 (25%)
Ugt37E1	NP_652628.2	YjiC	27..448	CDD:224732	115/459 (25%)
ugt-30	NP_506729.1	UDPGT	21..529	CDD:278624	132/538 (25%)
ugt-30	NP_506729.1	Glycosyltransferase_GTB_type	<255..524	CDD:299143	68/271 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910