Protein Alignment Ugt37E1 and ugt-66

DIOPT Version :10

• Sequence 1: NP_652628.2
• Gene: Ugt37E1 / 53512
• FlyBaseID: FBgn0040261
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_498344.3
• Gene: ugt-66 / 182814
• WormBaseID: WBGene00016013
• Length: 532
• Species: Caenorhabditis elegans
• Alignment Length: 560
• Identity: 132/560 - (23%)
• Similarity: 229/560 - (40%)
• Gaps: 91/560 - (16%)

  Fly     6 KIGFLIAFLLS-TMTQSSGGANILGVFGTHSPSHV--IVHMAVMKALADRGHNITVVTQMKPKLA 67
            ::..|..||:: |:|     .|:|.:......||:  :.|:|  ..|.:.|||:|.:
 Worm     3 RLHLLFLFLINQTLT-----INVLVLSPAFGGSHMNFMAHLA--DTLTEAGHNVTFL-------- 52

  Fly    68 THENITVIIAPPTEERQRYIKEYMAEVSNEKPSFWETMVKAIVQSSNQLEGQYEFMTH-PNVKEI 131
                  :.:|..|.:.|..:|.....|..|:.   |.|.:..:...:.::..:...|| ||.:|:
 Worm    53 ------IPVADETRKNQLGVKITKDVVLVEQD---EIMSRDTLIVDDHMDMMWTLDTHEPNFEEM 108

  Fly   132 Y---------------ENPKI-------KFDLVFLGLMANTYQLGIAAKLKCPVIISWVGIPL-P 173
            :               .|.::       .||:..|..: :...||...||.....|......| .
 Worm   109 FSWFNKIMELSCANFLRNTEVFELMKSRNFDVAILEPL-SVCGLGFFKKLGIEKTILASSCSLYD 172

  Fly   174 FMDTIVGNVNDPSYVPTVNVALNAGQKTMDFGLRFVNF-FKYAIMCVFETVLDYKMNQFYERAFA 237
            |:...:|...|.||||  :::..:|.: |.|..|:.|: |........:.:.| :....|.....
 Worm   173 FILPDIGEPEDHSYVP--SLSSQSGDQ-MSFYERYKNYRFSRDTKVTMDRMFD-RETAIYRAHLG 233

  Fly   238 NELEFPNYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQV---KEQADPLPKELAKFLDK 299
            .:|  |::..:....||.|.|.:...:.| ||.:.:::.||||.|   |.::..|.......||:
 Worm   234 KDL--PDWRVLLPSASLFFTNSNPYLDFP-RPVIQKTVAIGGISVNMGKIKSQKLDDHWDVILDQ 295

  Fly   300 ADEGAIFFSLGTNVNTNTFRPDTVDILYKVLSKLPQ-RVIWKWE--DLKNKPGNASNIFFGNWLP 361
            .:.. :..|.|:.|.::|...|....:.||:...|. ..|||:|  |.|...| ..|:.|..|:|
 Worm   296 RNNN-MLISFGSMVKSSTMPIDWKMNILKVIKSEPNVTFIWKYETNDTKFADG-VDNVHFSKWVP 358

  Fly   362 QDDILAHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMT---------KSGFGRW 417
            |..:|.......|:||.|.|...|..:.|.|.|.:||||||..||.::|         |:..|.:
 Worm   359 QTALLNDDRLTAFLTHGGLGSTNELAHWGKPAVTVPIFGDQVRNANMLTRHNGAIFVWKNDLGNY 423

  Fly   418 LDILTMTEHELEQTIREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHLQSP 482
                    ..:::.:.::|.|..|:......:.:..::|...:..|:..||::.:. |......|
 Worm   424 --------GIVKEAVHQILYNEKYKRNAKYLADILENQPHQPKDLVVKHTEFLAKF-GPFPKMDP 479

  Fly   483 LIHT-KFVARNNLDVYGVVLLVSLLLIVT----IKFLFRK 517
            ...: .|..||..|::..|:....:|...    :|||..|
 Worm   480 YGRSLNFFTRNLFDIHAAVVFTYFILATASFNILKFLLSK 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	GT1_Gtf-like	25..466	CDD:340817	113/482 (23%)
ugt-66	NP_498344.3	GT1_Gtf-like	19..464	CDD:340817	113/481 (23%)