Protein Alignment Ugt37E1 and ugt-49

DIOPT Version :10

• Sequence 1: NP_652628.2
• Gene: Ugt37E1 / 53512
• FlyBaseID: FBgn0040261
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_505666.2
• Gene: ugt-49 / 179446
• WormBaseID: WBGene00007070
• Length: 525
• Species: Caenorhabditis elegans
• Alignment Length: 548
• Identity: 148/548 - (27%)
• Similarity: 244/548 - (44%)
• Gaps: 78/548 - (14%)

  Fly     4 YTKIGFLIAFLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALADRGHNITV-VTQMKP--- 64
            ||   ||. .|||.:...:|  .||....:.|.||:|.:..:..||.|.||::.: :|:.:|
 Worm     2 YT---FLF-LLLSLLAVDAG--KILVYSPSISRSHLISNGRIADALVDAGHDVVMFITEYEPLTE 60

  Fly    65 -------KLATHENITVIIAPPTEERQRYIKEYMAEVSNEKPSFWETMV--KAIVQSSNQLEGQY 120
                   |:.|.:..:...|    |....|.||:  :|:.:.||.|.::  |....:.:.|..:.
 Worm    61 FTGTKKAKVITMKGFSTKFA----EDMDGIGEYL--LSSSRLSFLERLMFEKTCTGACDDLMTRR 119

  Fly   121 EFMTHPNVKEIYENPKIKFDLVFLGLMANTYQLGIAAKLKCPV-IISWVGI-------PLPFMDT 177
            |        |:.:.....||:.|      :.|:.:     |.| |:.::||       ..|.||.
 Worm   120 E--------ELEQLRAYNFDVAF------SEQIDL-----CGVGIVRYLGIKNHLWISTTPIMDA 165

  Fly   178 IVGNVNDP---SYVPTVNVALNAGQKTMDFGLRFVN-FFKYAIMCVFETVLDYKMNQFYERAFAN 238
            :..|:..|   |||||:....| |.| |||..|..| :.|...:.:.....|.....|  |.:..
 Worm   166 VSYNLGIPAPSSYVPTIEENDN-GDK-MDFWQRTFNLYMKIGSILIHRYGTDGTTEVF--RKYIP 226

  Fly   239 ELEFPNYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPKELAKFLDKADEG 303
              :|||..|:....||.|.|.....:.| |||:.::|.:||:.:.:.:.||.|:....:.|..||
 Worm   227 --DFPNVREIAANSSLCFVNSDEVLDLP-RPTITKAIYVGGLGIPKVSKPLDKKFTNIMSKGKEG 288

  Fly   304 AIFFSLGTNVNTNTFRPDTVDILYKVLSKLPQ-----RVIWKWEDLKNKPGNASNIFFGNWLPQD 363
            .:..|||:.:..........:.:.:.:.::..     ::.....:.|.......|:....||||.
 Worm   289 VVIISLGSIIPFGDLPAAAKEGVLRAIQEISDYHFLIKIAKGDNNTKKLVEGIKNVDVAEWLPQV 353

  Fly   364 DILAHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHEL 428
            |||:||..|||:.|.|..|:.|.....||.|.:|:|.||..|..::.|.|.|:.|..|.:.....
 Worm   354 DILSHPRLKLFVMHGGINGLVETAIQAVPTVIVPVFADQFRNGRMVEKRGIGKVLLKLDIGYESF 418

  Fly   429 EQTIREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGA---LHLQSPLIHTKFVA 490
            :.|:..||..|:|::...:...:.||:|.:..:.:..||::.:.| |.   ||::...::|  :.
 Worm   419 KNTVLTVLNTPSYKKNAIRIGKMMRDKPFSPEERLTKWTQFAIDH-GVLEELHVEGSRLNT--II 480

  Fly   491 RNNLDVYGVVLLVSL----LLIVTIKFL 514
            ..||||...||.|.:    :.|...|||
 Worm   481 YYNLDVIAFVLFVFVAVLHVFIYAFKFL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	GT1_Gtf-like	25..466	CDD:340817	122/470 (26%)
ugt-49	NP_505666.2	GT1_Gtf-like	18..443	CDD:340817	119/456 (26%)