Protein Alignment Ugt37E1 and UGT3A2

DIOPT Version :9

• Sequence 1: NP_652628.2
• Gene: Ugt37E1 / 53512
• FlyBaseID: FBgn0040261
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: XP_011512290.1
• Gene: UGT3A2 / 167127
• HGNCID: 27266
• Length: 550
• Species: Homo sapiens
• Alignment Length: 583
• Identity: 150/583 - (25%)
• Similarity: 257/583 - (44%)
• Gaps: 114/583 - (19%)

  Fly     6 KIGFLIAFLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALADRGHNITVVTQMK----PKL 66
            ::..|:.|||..:..|. .|.||.: .|...||.::...|.:.|.|.|||:|::...:    |.|
Human     5 RVLLLVGFLLPGVLLSE-AAKILTI-STVGGSHYLLMDRVSQILQDHGHNVTMLNHKRGPFMPGL 67

  Fly    67 ATHENITVIIAPPTEER-------QRYIKEYMAEVSNEKPSFWETMVKAIVQSSNQLE------- 117
            :.        :|.:..|       |:|.:..:.:...|:.|:  .::..:....:|.|
Human    68 SD--------SPASASRYPRILYLQKYCQFGLKDFKKEEKSY--QVISWLAPEDHQREFKKSFDF 122

  Fly   118 ---------GQYE---------------FMTHPNVKEIYENPKIKFDLVFLGLMANTYQ---LGI 155
                     |::|               |:...::.:..:|.  .||:|    :..|:.   ..|
Human   123 FLEETLGGRGKFENLLNVLEYLALQCSHFLNRKDIMDSLKNE--NFDMV----IVETFDYCPFLI 181

  Fly   156 AAKLKCP--VIISW------VGIPLPFMDTIVGNVNDPSYVPTVNVALNAGQKTMDFGLRFVNFF 212
            |.||..|  .|:|.      .|:|:|.           ||||.....|.   ..|||..|..||.
Human   182 AEKLGKPFVAILSTSFGSLEFGLPIPL-----------SYVPVFRSLLT---DHMDFWGRVKNFL 232

  Fly   213 KYAIMCVFETVLDYKMNQFYERAFANELEFPNYHEMKR--------RVSLLFYNYHSASEGPIRP 269
            .:...|        :..|..:..|.|.:: .::.|..|        :..|.|.|...|.:. .||
Human   233 MFFSFC--------RRQQHMQSTFDNTIK-EHFTEGSRPVLSHLLLKAELWFINSDFAFDF-ARP 287

  Fly   270 TVPQSIEIGGIQVKEQADPLPKELAKFLDK-ADEGAIFFSLGTNVNTNTFRPDTVDILYKVLSKL 333
            .:|.::.:||: :::...|:|::|..|:.| .|.|.:..:||:.||| ...|:....:....:.|
Human   288 LLPNTVYVGGL-MEKPIKPVPQDLENFIAKFGDSGFVLVTLGSMVNT-CQNPEIFKEMNNAFAHL 350

  Fly   334 PQRVIWKWEDLKNKPGN---ASNIFFGNWLPQDDILAHPNTKLFITHAGKGGVAEAQYHGVPMVA 395
            ||.||||.: ..:.|.:   |:|:...:||||.|:||||:.:||:||.|:..:.||..||||||.
Human   351 PQGVIWKCQ-CSHWPKDVHLAANVKIVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVG 414

  Fly   396 LPIFGDQQGNAEIMTKSGFGRWLDILTMTEHELEQTIREVLGNPAYRETIGKFSTLYRDRPLTAR 460
            :|:||||..|...:....||..:.:..:....|...:::::.:..|:......|.:.|..||:..
Human   415 IPLFGDQPENMVRVEAKKFGVSIQLKKLKAETLALKMKQIMEDKRYKSAAVAASVILRSHPLSPT 479

  Fly   461 QSVIYWTEYVLRHQGALHLQSPLIHTKFVARNNLDVYGVVLLVSLLLIVTIKFLFRKILNVAI 523
            |.::.|.::||:..||.||:..:....:..:..|||:  |.|:.|.|  ...:|..|:|.:|:
Human   480 QRLVGWIDHVLQTGGATHLKPYVFQQPWHEQYLLDVF--VFLLGLTL--GTLWLCGKLLGMAV 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	egt	7..475	CDD:223071	135/532 (25%)
		YjiC	27..448	CDD:224732	121/485 (25%)
UGT3A2	XP_011512290.1	UDPGT	23..518	CDD:278624	137/540 (25%)
		egt	<162..517	CDD:223071	111/389 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150563
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840