DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37E1 and Ugt3a1

DIOPT Version :9

Sequence 1:	NP_652628.2	Gene:	Ugt37E1 / 53512	FlyBaseID:	FBgn0040261	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_997099.2	Gene:	Ugt3a1 / 105887	MGIID:	2146055	Length:	523	Species:	Mus musculus

Alignment Length:	567	Identity:	148/567 - (26%)
Similarity:	253/567 - (44%)	Gaps:	100/567 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 FLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALADRGHNITV-------VTQMKPKLATHE 70
            |||..:...:  |.||.: .|.|.||.|:...|.:.|...||::..       :...:.:.::::
Mouse    13 FLLEVLLLEA--AKILTI-STLSASHYILMNRVSQILQGGGHDVIKLLYEGGDIPDFRKENSSYQ 74

  Fly    71 NITVIIAPPTEER------QRYIKEYMAEVSNEKPSFWETMVKAIVQSSNQLEGQY------EFM 123
            .|...: |..:::      .|.|.||....|.     :.|::|.         .||      ..:
Mouse    75 VINWRL-PEDQQKTFENRWHRLIDEYAYGRSK-----YHTLLKI---------HQYFADLCSHLL 124

  Fly   124 THPNVKEIYENPKIKFDLVFLGLMANTYQLGIAAKLKCPVIISWVGIPLPFMDTIVGNVNDP-SY 187
            :..::.|:.:  |..||||.|..| :.....|..||. ...:|::.....:||  .|..|.| ||
Mouse   125 SRKDIMELLQ--KENFDLVLLDSM-DLCSFLIVEKLG-KRFVSFLPFQFSYMD--FGLPNAPLSY 183

  Fly   188 VPTVNVALNAGQKTMDFGLRFVN---FFKYA-----IMCVF-ETVLDYKMNQFYERAFANELEFP 243
            .|.....|.   ..|||..|..|   ||.:.     |...: .||.::         || |...|
Mouse   184 APVYGSGLT---DQMDFWGRVKNILMFFHFTKKRRDIFSQYGNTVQEH---------FA-EGSQP 235

  Fly   244 NYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPKELAKFLDK-ADEGAIFF 307
            ...::..:..|.|.|...|.:. .||..|.::.:||: :.:...|:|::|..|:.: .|.|.:..
Mouse   236 VLSDLLLKAELWFVNSDFALDF-ARPLFPNTVYVGGL-LDKPVQPIPQDLEDFISQFGDSGFVLV 298

  Fly   308 SLGTNVNTNTFRPDTVDILYKVLSKLPQRVIW-----KW-EDLKNKPGNASNIFFGNWLPQDDIL 366
            :||:.|:....: :.:..:....:.|||.|:|     .| :|:...|    |:...:||||.|:|
Mouse   299 ALGSVVSMIQSK-EIIKEMNSAFAHLPQGVLWTCKSSHWPKDVSLAP----NVKIMDWLPQIDLL 358

  Fly   367 AHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHELEQT 431
            |||:.:||:||.|...|.||.:||||||.:|.||||..|...:.....|..:.:.|:.......|
Mouse   359 AHPSIRLFVTHGGMNSVMEAVHHGVPMVGIPFFGDQPENMVRVEAKNLGVSIQLQTLKAESFLLT 423

  Fly   432 IREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHL-----QSPLIHTKFVAR 491
            ::||:.:..|:........:.:..|||..|.::.|.:::|:..||.||     |.|. |.:::
Mouse   424 MKEVIEDQRYKTAAMASKVIRQSHPLTPAQRLVGWIDHILQTGGAAHLKPYAFQQPW-HEQYM-- 485

  Fly   492 NNLDVYGVVLLVSL-LLIVTIKFLFRKILNVAIGYGSQRKAVANKLK 537
              |||:..:|.::| .|.:::|.|      ||:   ::..:::.|:|
Mouse   486 --LDVFLFLLGLTLGTLWLSVKVL------VAV---TRYLSISRKVK 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	egt	7..475	CDD:223071	129/497 (26%)
Ugt37E1	NP_652628.2	YjiC	27..448	CDD:224732	119/456 (26%)
Ugt3a1	NP_997099.2	UDPGT	24..488	CDD:278624	133/510 (26%)
Ugt3a1	NP_997099.2	egt	<235..488	CDD:223071	77/264 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840601
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840