DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37E1 and ugt5f1

DIOPT Version :9

Sequence 1:	NP_652628.2	Gene:	Ugt37E1 / 53512	FlyBaseID:	FBgn0040261	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	XP_017207383.1	Gene:	ugt5f1 / 100415800	ZFINID:	ZDB-GENE-100406-6	Length:	556	Species:	Danio rerio

Alignment Length:	549	Identity:	163/549 - (29%)
Similarity:	259/549 - (47%)	Gaps:	62/549 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIEYTK-----IGFLIAFLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALADRGHNITVVT 60
            ::||..     |.|::..::.::|.......|| || .|..||.:....:::.|..|||.|:|:.
Zfish    23 LLEYINVFVMDIIFVVQIVVLSLTLPVHCGKIL-VF-PHEGSHWLNLNTLIEELHHRGHQISVIR 85

  Fly    61 QMK----PKLATHE---NITVIIAPPTEERQRYIKEYMAEVSNEKPSFWETMVKAIVQSSNQLEG 118
            .:.    |:.:.|.   |:..::.   .:.|.|......::...:...| |..|..::...:...
Zfish    86 ALDSWYIPETSPHYDSINVPFLLG---GDDQFYHSFIFRQLQIRREQRW-TRFKLDMELKEKFSE 146

  Fly   119 QY----EFMTHPNVKEIYENPKIK---FDLVFLGLMANTYQLGIAAKLKCPVI--ISWVGIPLPF 174
            .:    |.:.|...||.....:||   || :.|...||...:.:|..|..|::  :.|
Zfish   147 MHRKICEMVIHIVEKEPAIMKQIKEANFD-IMLTDPANGGGVVLAHYLHLPLVFNVQW------- 203

  Fly   175 MDTIVGNV------NDPSYVPTVNVALNAGQKTMDFGLRFVN-FFKYAIMCVFETVLDYKMNQFY 232
              |:.|..      :.|||||   ..|:....:|.|..|..| .|....:.::...:....:...
Zfish   204 --TVHGEAHFAIAPSPPSYVP---FPLSQLTDSMSFPQRIYNVLFSAVRLFLYRRTVGPHYSALC 263

  Fly   233 ERAFANELEFPNYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPKELAKFL 297
            .|.|...|:   |.|:.:...:.........:.| |||:|..|.|||... ..|..|||:|..||
Zfish   264 NRLFGPGLD---YFELFQAADIWLMRADFVFDFP-RPTMPNVIYIGGFHC-SPAKALPKDLEDFL 323

  Fly   298 DKADE-GAIFFSLGTNVNTNTFRPDTVDILYKVLSKLPQRVIWKWEDLKNKPGN-ASNIFFGNWL 360
            ..:.| |.|..||||.|  .....|..|.:....::|||:|||::..  ::|.| .:|....|||
Zfish   324 QSSGEHGVIVMSLGTLV--AQLPMDIADEIVAAFAELPQKVIWRYTG--DRPANVGNNTLLVNWL 384

  Fly   361 PQDDILAHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTE 425
            ||:|:|.||.|::|::|.|..||.||.|||||:|.||:..||..|...|...|..:.|||.|:..
Zfish   385 PQNDLLGHPKTRVFVSHGGTNGVFEAIYHGVPIVGLPLVFDQDYNLLKMKHKGVAKVLDIATINR 449

  Fly   426 HELEQTIREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHLQSPLIHTKFVA 490
            :..:..::|||.:|:||..:.|.|:|::|.||....|.::|||:|:||:||.||::......:.:
Zfish   450 NIFKDALQEVLNDPSYRSNMQKLSSLHKDTPLKPLDSALFWTEFVMRHRGAAHLRTDSYKMPWYS 514

  Fly   491 RNNLDVYGVVLLVSLLLIVTIKFLFRKIL 519
            .:::|| ||.|:..|..||   ||..||:
Zfish   515 YHSVDV-GVFLVSVLCFIV---FLMFKIV 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37E1	NP_652628.2	egt	7..475	CDD:223071	145/492 (29%)
Ugt37E1	NP_652628.2	YjiC	27..448	CDD:224732	129/445 (29%)
ugt5f1	XP_017207383.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584571
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.840