Protein Alignment Ugt37D1 and Ugt1a6a

DIOPT Version :9

• Sequence 1: NP_001285989.1
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_659545.2
• Gene: Ugt1a6a / 94284
• MGIID: 2137698
• Length: 531
• Species: Mus musculus
• Alignment Length: 559
• Identity: 165/559 - (29%)
• Similarity: 264/559 - (47%)
• Gaps: 71/559 - (12%)

  Fly    20 LLALQTMPQG----TEGANILG---VFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSSVP------ 71
            |.|.||:|.|    ...|::||   :......||::....|::.|:|:||::.|:  ||
Mouse     5 LPAAQTLPAGFLFLVLWASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIMVL--VPEVNLLL 67

  Fly    72 --PKVTHKSINHIVVPMSAEDEKVLNDG---------MAGMVKEKPSIWNTMKSIFSSL-ALLID 124
              .|...:.|..:...:.....:....|         :.|.::|..:....:...||:. :||.|
Mouse    68 GESKYYRRKIFSVTYSLEELQTRFRTFGNNHFLPGASLMGPLREYRNNMIVVDMFFSNCQSLLKD 132

  Fly   125 KQVDVLEDPRFQELYLNKGNKFDVVFV------GFFFNTYQVALGARFNCPVIISWSGPPMMMVN 183
            ...          |...:.||||.:|.      |       |.|....|.|.:..:.|.|..:.:
Mouse   133 SAT----------LSFLRENKFDALFTDPAMPCG-------VILAEYLNLPSVYLFRGFPCSLEH 180

  Fly   184 EVLGNPE-LSSVPQMHISAPPGQPMNFQQRMQNFASTLGFNALNIFLNHKYNKFYDRLWSKDKSM 247
            .:..:|. :|.||:.:...  ...|.|.||:.||...:..|.|...|..||......|..:|.|:
Mouse   181 MLGQSPSPVSYVPRFYTKF--SDHMTFPQRLANFIVNILENYLYYCLYSKYEIIASDLLKRDVSL 243

  Fly   248 PTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLE-KGKHGAIL 311
            |:..|.    ||.......:.|.| ||.:|.:|.:|||..|.| ..|.::.:.::. .|:||.::
Mouse   244 PSLHQN----SLWLLRYDFVFEYP-RPVMPNMIFLGGINCKKK-GKLTQEFEAYVNASGEHGIVV 302

  Fly   312 FSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWED--PKNTPGKSANILYKKWLPQDDILAHP 374
            |||||.:  ..|..:....|.:.|..:.|.|:|::..  |.|.   :.|.:..|||||:|:|.||
Mouse   303 FSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNL---AKNTILVKWLPQNDLLGHP 362

  Fly   375 KLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFKAAIKE 439
            |.:.||||:|..|:.|...:||||:.:|:|.||..||.::...|.|:.|.:..:..|:.:.|:|.
Mouse   363 KTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKT 427

  Fly   440 VIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVH-MNFIASNNLDIY- 502
            ||.|..|.:.:...|.|::|||:.|.:..|:|.|||:||.||.|:: |..| :.:...::||:.
Mouse   428 VINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIG 491

  Fly   503 IIAALVLYIVFIINKIVWKFVWRKLFGKSNKVSKGKKVK 541
            .:.|:||.:|||:.|.. .:..||.||...:|.|..|.|
Mouse   492 FLLAIVLTVVFIVFKCC-AYGCRKCFGGKGRVKKSHKSK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	150/523 (29%)
		UDPGT	45..530	CDD:278624	151/514 (29%)
Ugt1a6a	NP_659545.2	egt	15..503	CDD:223071	148/520 (28%)
		UDPGT	27..522	CDD:278624	152/528 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840728
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840