Protein Alignment Ugt37D1 and Ugt2b35

DIOPT Version :10

• Sequence 1: NP_652627.2
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001004271.1
• Gene: Ugt2b35 / 83808
• RGDID: 620895
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 531
• Identity: 159/531 - (29%)
• Similarity: 254/531 - (47%)
• Gaps: 66/531 - (12%)

  Fly    45 SHFIVHMSIMKTLAEKGHNVTVV---SSV--PPKVTHKSINHIVVPMSAEDEKVLNDGMAGMVKE 104
            ||::....|::.|.:|||.|||:   :||  .||.| ..:..:..|.|.....:.|     ....
  Rat    34 SHWMNIKIILEELVQKGHEVTVLRPSASVFLDPKET-SDLKFVTFPTSFSSHDLEN-----FFTR 92

  Fly   105 KPSIW------NTMKSIFSSLALLIDKQVD----VLEDPRFQELYLNK--GNKFDVVFVGFFFNT 157
            ..::|      :|..|.|..|...||:..|    |.::....:.::.|  .:||||||
  Rat    93 FVNVWTYELPRDTCLSYFLYLQDTIDEYSDYCLTVCKEAVSNKQFMTKLQESKFDVVF------- 150

  Fly   158 YQVALG-------ARFNCPVIISWSGPPMMMVNEVLGN---PELSSVPQMHISAPPGQPMNFQQR 212
             ..|:|       .....|.:.|....|...:.:.:|.   |. |.|| |..|...|| |.|.:|
  Rat   151 -SDAIGPCGELIAELLQIPFLYSLRFSPGYTIEKYIGGVLFPP-SYVP-MIFSGLAGQ-MTFIER 211

  Fly   213 MQNFASTLGFNA-LNIFLNHKYNKFYDRLWSKDKSMP-TFAQAKRNVSLAFCNGHGISEGPIRPN 275
            :.|....|.|:. ...|...|::.||    ||....| |.|:......:.....:...|.| .|.
  Rat   212 VHNMICMLYFDFWFQTFREKKWDPFY----SKTLGRPTTLAEIMGKAEMWLIRSYWDLEFP-HPI 271

  Fly   276 VPGVIEIGGIQVKSKPDPLPEDIQEFLE-KGKHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLK 339
            .|.|..|||:..| ...|||:||::|:: .|:||.::|||||.::  ::..|....|...|:.:.
  Rat   272 SPNVDYIGGLHCK-PAKPLPKDIEDFVQSSGEHGVVVFSLGSMVR--NMTEEKANIIAWALAQIP 333

  Fly   340 QQVIWKWEDPKNTPGKSANILYKKWLPQDDILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVF 404
            |:|:|:: |.|..|....|....|||||:|:|.|||.|.|:||.|..|:.||.:||:||:.:|:|
  Rat   334 QKVLWRF-DGKKPPTLGPNTRLYKWLPQNDLLGHPKTKAFVTHGGANGIYEAIHHGIPMIGIPLF 397

  Fly   405 ADQPGNADKLVASGYGLQLPLATLDVDEFKAAIKEVIENPKYAKTLKSFSQLYRDRPLSPQESVV 469
            .:|..|...:||.|..:::...|:...:...|::|||.||.|.|.....|.::.|:|..|.:..|
  Rat   398 GEQHDNIAHMVAKGAAVEVNFRTMSKSDMLNALEEVINNPFYKKNAMWLSTIHHDQPTKPLDRAV 462

  Fly   470 YWTEYVIRHHGAAHMQSPLVHMNFIASNNLDI--YIIAALVLYIVFIINKIVWKFVWRKLFGKSN 532
            :|.|:|:||.||.|::|...::.:...::||:  :::..:.:.:|..:.  .:.||:|..
  Rat   463 FWIEFVMRHKGAKHLRSLGHNLPWYQYHSLDVIGFLLTCVAVTVVLALK--CFLFVYRFF----- 520

  Fly   533 KVSKGKKVKKQ 543
             |.|.||.|.:
  Rat   521 -VKKEKKTKNE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_652627.2	GT1_Gtf-like	33..471	CDD:340817	139/455 (31%)
Ugt2b35	NP_001004271.1	UDPGT	24..527	CDD:278624	157/526 (30%)