Protein Alignment Ugt37D1 and UGT8

DIOPT Version :9

• Sequence 1: NP_001285989.1
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001121646.2
• Gene: UGT8 / 7368
• HGNCID: 12555
• Length: 541
• Species: Homo sapiens
• Alignment Length: 586
• Identity: 157/586 - (26%)
• Similarity: 250/586 - (42%)
• Gaps: 160/586 - (27%)

  Fly    44 PSHFIVHMSIMKTLA----EKGHNVTVVSS----VPPKVTHKSINHIVVPMSAEDEKVLNDGMAG 100
            |..|..||.|.||||    |:||:...:.|    :.|.      ||.
Human    28 PIMFESHMYIFKTLASALHERGHHTVFLLSEGRDIAPS------NHY------------------ 68

  Fly   101 MVKEKPSIWNT----------MKSIFSSLALLIDKQVDVLEDPRFQELYLNKGN----------K 145
            .::..|.|:|:          |::|||.....|: ..|:| |...:...|..||          |
Human    69 SLQRYPGIFNSTTSDAFLQSKMRNIFSGRLTAIE-LFDIL-DHYTKNCDLMVGNHALIQGLKKEK 131

  Fly   146 FDVVFV------GF-----------FFNT---YQVALGARFNCPVIISWSGPPMMMVNEVLGNPE 190
            ||::.|      ||           .|:|   |...:||    |.       |:..|      ||
Human   132 FDLLLVDPNDMCGFVIAHLLGVKYAVFSTGLWYPAEVGA----PA-------PLAYV------PE 179

  Fly   191 LSSVPQMHISAPPGQPMNFQQRMQN----FASTLGFNALNIFLNHKYNKFYDRLWSKDKSMPTFA 251
            .:|:..        ..||..|||:|    ..|.||.:.|.:       ..|:|:..|...:|
Human   180 FNSLLT--------DRMNLLQRMKNTGVYLISRLGVSFLVL-------PKYERIMQKYNLLP--- 226

  Fly   252 QAKRNVSLAFCNGHGIS----------EGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLE-KG 305
             .|....|.    ||.|          |.| ||.:|.|:.:|||..| ...|||||:|.::. ..
Human   227 -EKSMYDLV----HGSSLWMLCTDVALEFP-RPTLPNVVYVGGILTK-PASPLPEDLQRWVNGAN 284

  Fly   306 KHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWEDPK-NTPGKSANILYKKWLPQDD 369
            :||.:|.|.|:.:|  ::..::...:...|..|.|:|||::..|| ...|.:..::  :||||:|
Human   285 EHGFVLVSFGAGVK--YLSEDIANKLAGALGRLPQKVIWRFSGPKPKNLGNNTKLI--EWLPQND 345

  Fly   370 ILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFK 434
            :|.|.|:|.|::|.|...:.|..|||||::.:|:|.|......::.|.|.|:.|...|:...|..
Human   346 LLGHSKIKAFLSHGGLNSIFETIYHGVPVVGIPLFGDHYDTMTRVQAKGMGILLEWKTVTEKELY 410

  Fly   435 AAIKEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVHMNFIASNNL 499
            .|:.:||.||.|.:..:..|::::|:|..|....:||.:|:|||:||.|:::.:..::|.....|
Human   411 EALVKVINNPSYRQRAQKLSEIHKDQPGHPVNRTIYWIDYIIRHNGAHHLRAAVHQISFCQYFLL 475

  Fly   500 DIYIIAALVLYIVFIINKIVWKFVWRKL------------------------FGKSNKVSKGKKV 540
            ||..:..|...:::.:...|.||::||:                        :.::..:...|||
Human   476 DIAFVLLLGAALLYFLLSWVTKFIYRKIKSLWSRNKHSTVNGHYHNGILNGKYKRNGHIKHEKKV 540

  Fly   541 K 541
            |
Human   541 K 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	148/531 (28%)
		UDPGT	45..530	CDD:278624	152/572 (27%)
UGT8	NP_001121646.2	Glycosyltransferase_GTB-type	21..502	CDD:415824	151/545 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150688
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840