Protein Alignment Ugt37D1 and UGT2B15

DIOPT Version :9

• Sequence 1: NP_001285989.1
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001067.2
• Gene: UGT2B15 / 7366
• HGNCID: 12546
• Length: 530
• Species: Homo sapiens
• Alignment Length: 536
• Identity: 165/536 - (30%)
• Similarity: 267/536 - (49%)
• Gaps: 78/536 - (14%)

  Fly    45 SHFIVHMSIMKTLAEKGHNVTVVSSVPPKVTHKS----INHIVVPMS-----AEDE--KVLNDGM 98
            ||:|...:|::.|.::||.|||::|....:.:.|    |...|.|.|     .||.  |:|:..:
Human    34 SHWINMKTILEELVQRGHEVTVLTSSASTLVNASKSSAIKLEVYPTSLTKNYLEDSLLKILDRWI 98

  Fly    99 AGMVKEKPSIWNTMKSIFSSLALLIDKQVDVLEDPRFQELYLNK-------GNKFDVVFVGFFFN 156
            .|:.|      ||..|.||.|..|..:..| ..:...::..|||       .:||||:... ..|
Human    99 YGVSK------NTFWSYFSQLQELCWEYYD-YSNKLCKDAVLNKKLMMKLQESKFDVILAD-ALN 155

  Fly   157 TYQVALGARFNCPVIIS---------------WSGPPMMMVNEVLGNPELSSVPQMHISAPPGQP 206
            .....|...||.|.:.|               :..||             |.||.  :.:.....
Human   156 PCGELLAELFNIPFLYSLRFSVGYTFEKNGGGFLFPP-------------SYVPV--VMSELSDQ 205

  Fly   207 MNFQQRMQNFASTLGFNA-LNIFLNHKYNKFYDRLWSKDKSM-PTFAQAKRNVSLAFCNGHGISE 269
            |.|.:|::|....|.|:. ..|:...|:::||..:..:..:: .|..:|:..:...:.:    .|
Human   206 MIFMERIKNMIHMLYFDFWFQIYDLKKWDQFYSEVLGRPTTLFETMGKAEMWLIRTYWD----FE 266

  Fly   270 GPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLE-KGKHGAILFSLGSNLKGEHIQPEVVKTIFK 333
            .| ||.:|.|..:||:..| ...|||::::||:: .|::|.::|||||.:  .::..|....|..
Human   267 FP-RPFLPNVDFVGGLHCK-PAKPLPKEMEEFVQSSGENGIVVFSLGSMI--SNMSEESANMIAS 327

  Fly   334 GLSSLKQQVIWKWEDPK-NTPGKSANILYKKWLPQDDILAHPKLKLFITHAGKGGVAEAQYHGVP 397
            .|:.:.|:|:|:::..| ||.|.:.. || |||||:|:|.|||.|.||||.|..|:.||.|||:|
Human   328 ALAQIPQKVLWRFDGKKPNTLGSNTR-LY-KWLPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIP 390

  Fly   398 MLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFKAAIKEVIENPKYAKTLKSFSQLYRDRPL 462
            |:.:|:||||..|...:.|.|..|.:.:.|:...:...|:|.||.:|.|.:.:...|:::.|:|:
Human   391 MVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSVINDPVYKENVMKLSRIHHDQPM 455

  Fly   463 SPQESVVYWTEYVIRHHGAAHMQSPLVHMNFIASNNLD-IYIIAALVLYIVFIINKIVWKFVWRK 526
            .|.:..|:|.|:|:||.||.|::....::.:|..::|| |..:.|.|..::|||.|.. .|.:||
Human   456 KPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWIQYHSLDVIAFLLACVATVIFIITKFC-LFCFRK 519

  Fly   527 LFGKSNKVSKGKKVKK 542
            |      ..||||.|:
Human   520 L------AKKGKKKKR 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	152/504 (30%)
		UDPGT	45..530	CDD:278624	160/522 (31%)
UGT2B15	NP_001067.2	egt	8..508	CDD:223071	152/506 (30%)
		UDPGT	24..518	CDD:278624	157/517 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150298
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840