Protein Alignment Ugt37D1 and UGT2B10

DIOPT Version :9

• Sequence 1: NP_001285989.1
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001066.1
• Gene: UGT2B10 / 7365
• HGNCID: 12544
• Length: 528
• Species: Homo sapiens
• Alignment Length: 529
• Identity: 143/529 - (27%)
• Similarity: 246/529 - (46%)
• Gaps: 79/529 - (14%)

  Fly    52 SIMKTLAEKGHNVTVVSS------------------VPPKVTHKSINHIVVPMSAEDEKVLNDGM 98
            :|:|.|.::||.|||::|                  .|..:|.....:|::.:.....::..|..
Human    40 TILKELVQRGHEVTVLASSASILFDPNDSSTLKLEVYPTSLTKTEFENIIMQLVKRLSEIQKDTF 104

  Fly    99 -AGMVKEKPSIW-------NTMKSIFSSLALLIDKQVDVLEDPRFQELYLNKGNKFDVVFVGFFF 155
             ....:|:..:|       |..|.:.|:..|:          .:.||      ::||:||...:.
Human   105 WLPFSQEQEILWAINDIIRNFCKDVVSNKKLM----------KKLQE------SRFDIVFADAYL 153

  Fly   156 NTYQVALGARFNCPVIISWSGPPMMMVNEVLGN----PELSSVPQMHISAPPGQPMNFQQRMQNF 216
            ...:: |...||.|.:.|.|..|........|.    |....|....:|    ..|.|.:|::|.
Human   154 PCGEL-LAELFNIPFVYSHSFSPGYSFERHSGGFIFPPSYVPVVMSKLS----DQMTFMERVKNM 213

  Fly   217 ASTLGFNA-LNIFLNHKYNKFYDRLWSKDKSMPTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVI 280
            ...|.|:. ..||...|:::||..:..:.   .|.::..|...:.........:.| .|.:|.|.
Human   214 LYVLYFDFWFQIFNMKKWDQFYSEVLGRP---TTLSETMRKADIWLMRNSWNFKFP-HPFLPNVD 274

  Fly   281 EIGGIQVKSKPDPLPEDIQEFLE-KGKHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIW 344
            .:||:..| ...|||::::||:: .|::|.::|||||.:  .::..|....|...|:.:.|:|:|
Human   275 FVGGLHCK-PAKPLPKEMEEFVQSSGENGVVVFSLGSMV--SNMTEERANVIATALAKIPQKVLW 336

  Fly   345 KWEDPKNTP-GKSANILYKKWLPQDDILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQP 408
            :::.  |.| ....|....||:||:|:|.|||.:.||||.|..|:.||.|||:||:.:|:|.|||
Human   337 RFDG--NKPDALGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQP 399

  Fly   409 GNADKLVASGYGLQLPLATLDVDEFKAAIKEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTE 473
            .|...:.|.|..:::...|:...:...|:|.||.:|.|.:.:...|::..|:|:.|.:..|:|.|
Human   400 DNIAHMKAKGAAVRVDFNTMSSTDLLNALKTVINDPSYKENIMKLSRIQHDQPVKPLDRAVFWIE 464

  Fly   474 YVIRHHGAAHMQSPLVHMNFIASNNLDIY-IIAALVLYIVFIINK----IVWKFVWRKLFGKSNK 533
            :|:||.||.|::....::.:...::||:. .:.|.|..::|||.|    ..|||
Human   465 FVMRHKGAKHLRVAAHNLTWFQYHSLDVIGFLLACVATVLFIITKCCLFCFWKF----------- 518

  Fly   534 VSKGKKVKK 542
            ..||||.|:
Human   519 ARKGKKGKR 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	131/493 (27%)
		UDPGT	45..530	CDD:278624	138/515 (27%)
UGT2B10	NP_001066.1	UDPGT	23..524	CDD:278624	140/524 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150538
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840