Protein Alignment Ugt37D1 and UGT2B7

DIOPT Version :9

• Sequence 1: NP_001285989.1
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001065.2
• Gene: UGT2B7 / 7364
• HGNCID: 12554
• Length: 529
• Species: Homo sapiens
• Alignment Length: 530
• Identity: 146/530 - (27%)
• Similarity: 257/530 - (48%)
• Gaps: 72/530 - (13%)

  Fly    45 SHFIVHMSIMKTLAEKGHNVTVVSS------------------VPPKVTHKSINHIVVPMSAEDE 91
            ||::...:|:..|.::||.|||::|                  .|..:|...:.:.::    :..
Human    34 SHWMNIKTILDELIQRGHEVTVLASSASILFDPNNSSALKIEIYPTSLTKTELENFIM----QQI 94

  Fly    92 KVLNDGMAGMVKEKPSIW------NTMKSIFSSLALLIDKQVDVLEDPRFQELYLNKGNKFDVVF 150
            |..:|      ..|.:.|      ..:.|||..:.....|  ||:.:.:|.:..  :.::|||:|
Human    95 KRWSD------LPKDTFWLYFSQVQEIMSIFGDITRKFCK--DVVSNKKFMKKV--QESRFDVIF 149

  Fly   151 VGFFFNTYQVALGARFNCPVIISWSGPPMMMVNEVLGN----PELSSVPQMHISAPPGQPMNFQQ 211
            ....|...:: |...||.|.:.|.|..|.....:..|.    |....|....::    ..|.|.:
Human   150 ADAIFPCSEL-LAELFNIPFVYSLSFSPGYTFEKHSGGFIFPPSYVPVVMSELT----DQMTFME 209

  Fly   212 RMQNFASTLGFNA-LNIFLNHKYNKFYDRLWSKDKSMPTFAQAKRNVSLAFCNGHGISEGPIRPN 275
            |::|....|.|:. ..||...|:::||..:..:..:: :....|.:|.|...:.:.....|:.||
Human   210 RVKNMIYVLYFDFWFEIFDMKKWDQFYSEVLGRPTTL-SETMGKADVWLIRNSWNFQFPYPLLPN 273

  Fly   276 VPGVIEIGGIQVKSKPDPLPEDIQEFLE-KGKHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLK 339
            |..|   ||:..| ...|||:::::|:: .|::|.::|||||.:  .::..|....|...|:.:.
Human   274 VDFV---GGLHCK-PAKPLPKEMEDFVQSSGENGVVVFSLGSMV--SNMTEERANVIASALAQIP 332

  Fly   340 QQVIWKWEDPK-NTPGKSANILYKKWLPQDDILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPV 403
            |:|:|:::..| :|.|.:.. || ||:||:|:|.|||.:.||||.|..|:.||.|||:||:.:|:
Human   333 QKVLWRFDGNKPDTLGLNTR-LY-KWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPL 395

  Fly   404 FADQPGNADKLVASGYGLQLPLATLDVDEFKAAIKEVIENPKYAKTLKSFSQLYRDRPLSPQESV 468
            |||||.|...:.|.|..:::...|:...:...|:|.||.:|.|.:.:...|::..|:|:.|.:..
Human   396 FADQPDNIAHMKARGAAVRVDFNTMSSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRA 460

  Fly   469 VYWTEYVIRHHGAAHMQSPLVHMNFIASNNLDIY-IIAALVLYIVFIINK----IVWKFVWRKLF 528
            |:|.|:|:||.||.|::.....:.:...::||:. .:...|..::||:.|    ..|||
Human   461 VFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLVCVATVIFIVTKCCLFCFWKF------ 519

  Fly   529 GKSNKVSKGK 538
              :.|..|||
Human   520 --ARKAKKGK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	136/498 (27%)
		UDPGT	45..530	CDD:278624	142/520 (27%)
UGT2B7	NP_001065.2	UDPGT	24..525	CDD:278624	143/526 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150469
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840