Protein Alignment Ugt37D1 and Ugt1a8

DIOPT Version :10

• Sequence 1: NP_652627.2
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001365304.1
• Gene: Ugt1a8 / 613123
• MGIID: 3576090
• Length: 530
• Species: Mus musculus
• Alignment Length: 543
• Identity: 157/543 - (28%)
• Similarity: 250/543 - (46%)
• Gaps: 96/543 - (17%)

  Fly    45 SHFIVHMSIMKTLAEKGHNVTVVSSVPPKVTH--KSINHIVVPMSA------------------- 88
            ||:.....|::.|:.:||.|.||  :|....|  ||.|..|...|.
Mouse    36 SHWFSMKMIVEKLSHRGHEVVVV--IPEVSWHLGKSQNFTVKTYSVSYTLEDLSHHFNFFAHKQW 98

  Fly    89 EDEKVLNDGMAGMVKEKPS-----IWNTMKSIFSSLALLIDKQVDVLEDPRFQELYLNKGNKFD- 147
            |:.:|   ||..::|....     :::..:|:|:.     .|.|:.|:...|..::|   :.||
Mouse    99 ENREV---GMFSLLKHSGKGFFQVLFSHCRSLFND-----KKLVEYLKQRSFDAVFL---DPFDV 152

  Fly   148 -------------VVFVGFFFNTYQVALGARFNCPVIISWSGPPMMMVNEVLGNPELSSVPQMHI 199
                         |||.|..|..|   |.....||      .||             |.||:  |
Mouse   153 CGLTIAKYFSLPSVVFSGGIFCHY---LDEGAQCP------SPP-------------SYVPR--I 193

  Fly   200 SAPPGQPMNFQQRMQNFASTLGFNALNIFLNHKYNKFYDRLWSKDKSMP-TFAQAKRNVSLAFCN 263
            .:.....|.|::|:.|:.|.:...|...:    :.|....:.|:....| |......:||:....
Mouse   194 LSKFADTMTFKERVWNYFSYMKERAFCPY----FFKTAIEIASEVLQTPVTMTDLFSSVSIWMFR 254

  Fly   264 GHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLE-KGKHGAILFSLGSNLKGEHIQPEV 327
            ...:.|.| ||.:|.::.||||.. ....||.::.:.::. .|:||.::|||||.:  ..|..:.
Mouse   255 TDFVLEFP-RPVMPNMVYIGGINC-HPGKPLSKEFEAYVNASGEHGIVVFSLGSMV--SEIPEKK 315

  Fly   328 VKTIFKGLSSLKQQVIWKWED--PKNTPGKSANILYKKWLPQDDILAHPKLKLFITHAGKGGVAE 390
            ...|.:.|..:.|.|:|::..  |.|.   :.|.:..|||||:|:|.|||.:.||||:|..|:.|
Mouse   316 AMEIAEALGRIPQTVLWRYTGTRPSNL---AKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYE 377

  Fly   391 AQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFKAAIKEVIENPKYAKTLKSFSQ 455
            ...:||||:.:|:|.||..||.::...|.|:.|.:..:..|:.:.|:|.||.|..|.:.:...|.
Mouse   378 GICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSS 442

  Fly   456 LYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVH-MNFIASNNLDIY-IIAALVLYIVFIINKI 518
            |::|||:.|.:..|:|.|||:||.||.|:: |..| :.:...::||:. .:.|:||.:|||:.|.
Mouse   443 LHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKC 506

  Fly   519 VWKFVWRKLFGKSNKVSKGKKVK 541
            . .:..||.||...:|.|..|.|
Mouse   507 C-AYGCRKCFGGKGRVKKSHKSK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_652627.2	GT1_Gtf-like	33..471	CDD:340817	129/469 (28%)
Ugt1a8	NP_001365304.1	UDPGT	26..521	CDD:278624	153/534 (29%)