Protein Alignment Ugt37D1 and Ugt1a5

DIOPT Version :9

• Sequence 1: NP_001285989.1
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001034638.1
• Gene: Ugt1a5 / 574523
• RGDID: 1583689
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 561
• Identity: 156/561 - (27%)
• Similarity: 262/561 - (46%)
• Gaps: 68/561 - (12%)

  Fly    12 SLGGLLVALLALQTMPQGTEGANILGVFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSSVPPKVTH 76
            :|.||...||.|..:| ..||..:| ||.... ||::....:::.|..:||...|::   |:||
  Rat     6 TLQGLAGLLLLLYALP-WAEGGKVL-VFPMEG-SHWLSMRDVVRELHARGHQAVVLA---PEVT- 63

  Fly    77 KSINHIVVPMSAEDEKVLNDGMAGMVKE--KPSIWNTMKSIFSS-----------------LALL 122
                   |.:..||...|........::  :..:...:|.:|.:                 ..:|
  Rat    64 -------VHIKEEDFFTLQTYPVPYTRQGFRQQMMRNIKVVFETGNYVKTFLETSEILKNISTVL 121

  Fly   123 IDKQVDVLEDPRFQELYLNKGNKFDVVFVGFFFNTYQVALGARFNCPVIISWSGPPMMMVNEVLG 187
            :...:::|.:....: :|| .:.||:|..........| |......|.:......|..:.:|...
  Rat   122 LRSCMNLLHNGSLLQ-HLN-SSSFDMVLTDPVIPCGAV-LAKYLGIPTVFFLRYIPCGIDSEATQ 183

  Fly   188 NPELSS-VPQM------HISAPPGQPMNFQQRMQNFASTLGFNALNIFLNHKYNKFYDRLWSKDK 245
            .|:.|| :|.:      |        |.|.||::|....|....:..|...:|......|..::.
  Rat   184 CPKPSSYIPNLLTMLSDH--------MTFLQRVKNMLYPLALKYICHFSFTRYESLASELLQREV 240

  Fly   246 SMPTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLE-KGKHGA 309
            |:   .:...:.|:....|..:.:.| ||.:|.::.||||....| .||.::.:.::. .|:||.
  Rat   241 SL---VEVLSHASVWLFRGDFVFDYP-RPVMPNMVFIGGINCVIK-KPLSQEFEAYVNASGEHGI 300

  Fly   310 ILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWED--PKNTPGKSANILYKKWLPQDDILA 372
            ::|||||.:  ..|..:....|.:.|..:.|.|:|::..  |.|.   :.|.:..|||||:|:|.
  Rat   301 VVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNL---AKNTILVKWLPQNDLLG 360

  Fly   373 HPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFKAAI 437
            |||.:.||||:|..|:.|...:||||:.:|:|.||..||.::...|.|:.|.:..:..|:.:.|:
  Rat   361 HPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENAL 425

  Fly   438 KEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVH-MNFIASNNLDI 501
            |.||.|..|.:.:...|.|::|||:.|.:..|:|.|||:||.||.|:: |..| :.:...::||:
  Rat   426 KTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDV 489

  Fly   502 Y-IIAALVLYIVFIINKIVWKFVWRKLFGKSNKVSKGKKVK 541
            . .:.|:||.:|||:.|.. .:..||.||...:|.|..|.|
  Rat   490 IGFLLAIVLTVVFIVYKSC-AYGCRKCFGGKGRVKKSHKSK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	138/517 (27%)
		UDPGT	45..530	CDD:278624	139/515 (27%)
Ugt1a5	NP_001034638.1	UDPGT	26..522	CDD:278624	143/531 (27%)
		egt	<259..505	CDD:223071	91/253 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344058
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.840