DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37D1 and ugt5g1

DIOPT Version :9

Sequence 1:	NP_001285989.1	Gene:	Ugt37D1 / 53511	FlyBaseID:	FBgn0040260	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_001107914.1	Gene:	ugt5g1 / 570913	ZFINID:	ZDB-GENE-080305-10	Length:	528	Species:	Danio rerio

Alignment Length:	573	Identity:	157/573 - (27%)
Similarity:	259/573 - (45%)	Gaps:	94/573 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 STWIGCSLGGLLVALLALQTMPQGTEGANILGVFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSSV 70
            |.|        |.||..|.::.....|.||| ||.... ||::....|::.|...||:.|||.|.
Zfish     5 SKW--------LSALTCLLSVVCCCHGGNIL-VFPEDG-SHWVNMQVILRKLHTHGHSFTVVRSS 59

  Fly    71 PPKVTHKS---INHIVV-PMSAEDE-----KVLNDGMAGMVKEKPSI--WNTMKSIFSSL----- 119
            .....|::   .|.|.| |:..||.     .:|.|....:.|..|.:  :...|.|.:.|
Zfish    60 KSWYIHENSALYNTITVNPVETEDVGQDYFNMLLDRSLALQKMSPLVRFFEQQKDITTVLKVFHN 124

  Fly   120 -------ALLIDKQ-VDVLEDPRFQELYLNKGNKFDVVFVGFFFNTYQVALGARFNCPVI--ISW 174
                   |:|.|.: |..|.:.:|..|..:......|:...|            ...|::  :.|
Zfish   125 GVLRMVSAMLDDAELVKSLREAKFDLLLTDPAFPAGVLVANF------------LQLPMVYNVRW 177

  Fly   175 SGPPMMMVNEVLGNPELSSVPQMHISAPPG----------QPMNFQQRMQNFASTLGFNALNIFL 229
            ..         .|:..:.:.|     :||.          ..|:|.||::||     ...|...|
Zfish   178 LN---------AGDAHMQTAP-----SPPSYVPMYNSLLHDQMSFLQRVENF-----LRYLCSLL 223

  Fly   230 NHK------YNKFYDRLWSKDKSMPTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVK 288
            ..:      |.:..:|.:.....:.:..|   :..:.......:.:.| ||.:|.:|.:||.|.|
Zfish   224 QERYVIVPIYRELLERHFPPGSDLLSMQQ---SADIWLMRMDFVFDFP-RPTMPNIIYMGGFQCK 284

  Fly   289 SKPDPLPEDIQEFLE-KGKHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWEDPK-N 351
             ....||.|::||:: .|:||.:..|||:.:..  :...:.:.|....:.:.|:|:|::...: :
Zfish   285 -PAQALPVDLEEFMQSSGEHGVVFMSLGAMVGA--LPRTITEAIASAFAKIPQKVMWRYHGERPS 346

  Fly   352 TPGKSANILYKKWLPQDDILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVA 416
            |.|.  |.|..:|.||:|:|.|||.:.|::|.|..|:.||.|||||:||||:..||..|..:|..
Zfish   347 TLGN--NTLLLEWFPQNDLLGHPKTRAFVSHGGTNGIYEAIYHGVPVLALPLLFDQFDNVMRLQV 409

  Fly   417 SGYGLQLPLATLDVDEFKAAIKEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGA 481
            ......|.:|||...||...:|:|:|||.|..:::..|:|:||:|:||.:|..:|.|||:||.||
Zfish   410 RNAARVLQVATLTSQEFLEGLKDVLENPLYRSSIRKMSELHRDQPISPLDSATFWIEYVMRHKGA 474

  Fly   482 AHMQSPLVHMNFIASNNLDIYIIAALVLYIVFIINKIVWKFVWRKLFGKSNKV 534
            ||::|...::.:.:.::||:.:....:..|.|..:..|.:|:..:...|..||
Zfish   475 AHLRSEANNLAWYSYHSLDVLVFLLAIAVIAFWTSVYVCRFLCCRKSIKKRKV 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	144/530 (27%)
Ugt37D1	NP_001285989.1	UDPGT	45..530	CDD:278624	142/528 (27%)
ugt5g1	NP_001107914.1	UDPGT	24..526	CDD:278624	148/543 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584661
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.840