Protein Alignment Ugt37D1 and UGT2B28

DIOPT Version :9

• Sequence 1: NP_001285989.1
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_444267.1
• Gene: UGT2B28 / 54490
• HGNCID: 13479
• Length: 529
• Species: Homo sapiens
• Alignment Length: 548
• Identity: 143/548 - (26%)
• Similarity: 251/548 - (45%)
• Gaps: 103/548 - (18%)

  Fly    45 SHFIVHMSIMKTLAEKGHNVTVVSS------------------VPPKVTHKSINHIVVPMSAEDE 91
            ||::...:|:|.|.::||.|||::|                  .|..:|.....:|::    :..
Human    34 SHWMNMKTILKELVQRGHEVTVLASSASILFDPNDAFTLKLEVYPTSLTKTEFENIIM----QQV 94

  Fly    92 KVLNDGMAGMVKEKPSIWNTMKSIFSSLALLIDKQVDVLEDPRFQELYLN--------------- 141
            |..:|      .:|.|.|           |...::.::|.:  |.:::.|
Human    95 KRWSD------IQKDSFW-----------LYFSQEQEILWE--FHDIFRNFCKDVVSNKKVMKKL 140

  Fly   142 KGNKFDVVFVGFFFNTYQVALGARFNCPVIISWSGPPMMMVNEVLGN----PELSSVPQMHISAP 202
            :.::||::|...||...:: |.|..|.|.:.|....|...:....|.    |....|....:|
Human   141 QESRFDIIFADAFFPCGEL-LAALLNIPFVYSLCFTPGYTIERHSGGLIFPPSYIPVVMSKLS-- 202

  Fly   203 PGQPMNFQQRMQNFASTLGFNA-LNIFLNHKYNKFYDRLWSKDKSM-PTFAQA----KRNVSLAF 261
              ..|.|.:|::|....|.|:. ..:....|:::||..:..:..:: .|..:|    .|| |.:|
Human   203 --DQMTFMERVKNMIYVLYFDFWFQMCDMKKWDQFYSEVLGRPTTLFETMGKADIWLMRN-SWSF 264

  Fly   262 CNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLE-KGKHGAILFSLGSNLKGEHIQP 325
            ...|        |.:|.:..:||:..| ...|||::::||:: .|::|.::|||||.:  .::..
Human   265 QFPH--------PFLPNIDFVGGLHCK-PAKPLPKEMEEFVQSSGENGVVVFSLGSVI--SNMTA 318

  Fly   326 EVVKTIFKGLSSLKQQVIWKWEDPKNTP-GKSANILYKKWLPQDDILAHPKLKLFITHAGKGGVA 389
            |....|...|:.:.|:|:|:::.  |.| ....|....||:||:|:|..||.:.||||.|..|:.
Human   319 ERANVIATALAKIPQKVLWRFDG--NKPDALGLNTRLYKWIPQNDLLGLPKTRAFITHGGANGIY 381

  Fly   390 EAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFKAAIKEVIENPKYAKTLKSFS 454
            ||.|||:||:.:|:|.|||.|...:.|.|..::|...|:...:...|:|.||.:|.|.:.:...|
Human   382 EAIYHGIPMVGIPLFWDQPDNIAHMKAKGAAVRLDFHTMSSTDLLNALKTVINDPSYKENVMKLS 446

  Fly   455 QLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVHMNFIASNNLDIY-IIAALVLYIVFIINKI 518
            .:..|:|:.|....|:|.|:|:.|.||.|::.....:.:...::||:. .:.|.|..::|::.|.
Human   447 IIQHDQPVKPLHRAVFWIEFVMCHKGAKHLRVAARDLTWFQYHSLDVIGFLLACVATVIFVVTKF 511

  Fly   519 ----VWKFVWRKLFGKSNKVSKGKKVKK 542
                .|||           ..||||.|:
Human   512 CLFCFWKF-----------ARKGKKGKR 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	133/512 (26%)
		UDPGT	45..530	CDD:278624	138/534 (26%)
UGT2B28	NP_444267.1	UDPGT	24..525	CDD:278624	140/543 (26%)
		egt	<269..506	CDD:223071	79/241 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150540
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840