Protein Alignment Ugt37D1 and Ugt1a1

DIOPT Version :9

• Sequence 1: NP_001285989.1
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_964007.2
• Gene: Ugt1a1 / 394436
• MGIID: 98898
• Length: 535
• Species: Mus musculus
• Alignment Length: 573
• Identity: 152/573 - (26%)
• Similarity: 252/573 - (43%)
• Gaps: 98/573 - (17%)

  Fly    16 LLVALLALQTMPQGTEGANILGVFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSSVPPKVTH---- 76
            ||:..|.|.........|..|.||.... ||::..:.:::.|.:|||.|.|::  |....|
Mouse    12 LLLPYLLLCVFGPSASHAGRLLVFPMDG-SHWLSMLGVIQQLQQKGHEVVVIA--PEASIHIKEG 73

  Fly    77 --KSINHIVVPMSAE--------------------------------DEKVLNDGMAGMVKEKPS 107
              .::....||...|                                |..:|..|.:.::.....
Mouse    74 SFYTLRKFPVPFQKENVTATLVELGRTAFNQDSFLLRVVKIYMKVKRDSSMLLAGCSHLLHNAEF 138

  Fly   108 IWNTMKSIFSSLALLIDKQVDVLEDPRFQELYLNKGN---KFDVVFVGFFFNTYQVALGAR-FNC 168
            :.:..:|.|.:|          |.||     :|..|:   ::..|...:|.|....:|.:. ..|
Mouse   139 MASLEESHFDAL----------LTDP-----FLPCGSIVAQYLTVPTVYFLNKLPCSLDSEATQC 188

  Fly   169 PVIISWSGPPMMMVNEVLGNPELSSVPQMHISAPPGQPMNFQQRMQNFASTLGFNALNIFLNHKY 233
            ||.:|:. |..:..|                    ...|||.||::|....:..|.:...:...|
Mouse   189 PVPLSYV-PKSLSFN--------------------SDRMNFLQRVKNVLLAVSENFMCRVVYSPY 232

  Fly   234 NKFYDRLWSKDKSMPTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDI 298
            ......:..|:.::......   .|:.......:.:.| ||.:|.::.||||....| .||.::.
Mouse   233 GSLATEILQKEVTVQDLLSP---ASIWLMRSDFVKDYP-RPIMPNMVFIGGINCLQK-KPLSQEF 292

  Fly   299 QEFLE-KGKHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWED--PKNTPGKSANIL 360
            :.::. .|:||.::|||||.:  ..|..:....|.:.|..:.|.|:|::..  |.|.   :.|.:
Mouse   293 EAYVNASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNL---AKNTI 352

  Fly   361 YKKWLPQDDILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPL 425
            ..|||||:|:|.|||.:.||||:|..|:.|...:||||:.:|:|.||..||.::...|.|:.|.:
Mouse   353 LVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNV 417

  Fly   426 ATLDVDEFKAAIKEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVH 490
            ..:..|:.:.|:|.||.|..|.:.:...|.|::|||:.|.:..|:|.|||:||.||.|:: |..|
Mouse   418 LEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAH 481

  Fly   491 -MNFIASNNLDIY-IIAALVLYIVFIINKIVWKFVWRKLFGKSNKVSKGKKVK 541
             :.:...::||:. .:.|:||.:|||:.|.. .:..||.||...:|.|..|.|
Mouse   482 DLTWYQYHSLDVIGFLLAIVLTVVFIVFKCC-AYGCRKCFGGKGRVKKSHKSK 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	136/533 (26%)
		UDPGT	45..530	CDD:278624	139/531 (26%)
Ugt1a1	NP_964007.2	egt	20..507	CDD:223071	137/536 (26%)
		UDPGT	30..526	CDD:278624	143/546 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840325
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840