Protein Alignment Ugt37D1 and Ugt1a6b

DIOPT Version :9

• Sequence 1: NP_001285989.1
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_958812.3
• Gene: Ugt1a6b / 394435
• MGIID: 3580629
• Length: 531
• Species: Mus musculus
• Alignment Length: 561
• Identity: 171/561 - (30%)
• Similarity: 269/561 - (47%)
• Gaps: 75/561 - (13%)

  Fly    20 LLALQTMPQG----TEGANILG---VFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSSVP------ 71
            |.|.||:|.|    ...|::||   :......||::....|::.|:|:||::.|:  ||
Mouse     5 LPAAQTLPAGFLFLVLWASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIVVL--VPEVNLLL 67

  Fly    72 --PKVTHKSINHIVVPMSAED-----------EKVLNDGMAGMVKEKPSIWNTMKSIFSSL-ALL 122
              .|...:.|  ..||.|.|:           :.|....:.|.::|..:...|::..||:. :||
Mouse    68 GESKYYRRKI--FSVPYSLEELQTRFRTFGRNQFVPGAPLMGPLREYRNSMLTLEMFFSNCQSLL 130

  Fly   123 IDKQVDVLEDPRFQELYLNKGNKFDVVFV------GFFFNTYQVALGARFNCPVIISWSGPPMMM 181
            .|...          |...:.||||.:|.      |       |.|....|.|.:..:.|.|..:
Mouse   131 KDSAT----------LSFLRENKFDALFTDPAMPCG-------VILAEYLNLPSVYLFRGFPCSL 178

  Fly   182 VNEVLGNPE-LSSVPQMHISAPPGQPMNFQQRMQNFASTLGFNALNIFLNHKYNKFYDRLWSKDK 245
            .:.:..:|. :|.||:.:...  ...|.|.||:.||...:..|.|...|..||......|..:|.
Mouse   179 EHMLGQSPSPVSYVPRFYTKF--SDHMTFPQRLANFIVNILENYLYYCLYSKYEIIVTDLLKRDV 241

  Fly   246 SMPTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLE-KGKHGA 309
            |:|:..|.    ||.......:.|.| ||.:|.:|.||||..|.| ..|.::.:.::. .|:||.
Mouse   242 SLPSLHQN----SLWLLRYDFVFEYP-RPIMPNMIFIGGINCKKK-GKLTQEFEAYVNASGEHGI 300

  Fly   310 ILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWED--PKNTPGKSANILYKKWLPQDDILA 372
            ::|||||.:  ..|..:....|.:.|..:.|.|:|::..  |.|.   :.|.:..|||||:|:|.
Mouse   301 VVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNL---AKNTILVKWLPQNDLLG 360

  Fly   373 HPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFKAAI 437
            |||.:.||||:|..|:.|...:||||:.:|:|.||..||.::...|.|:.|.:..:..|:.:.|:
Mouse   361 HPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENAL 425

  Fly   438 KEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVH-MNFIASNNLDI 501
            |.||.|..|.:.:...|.|::|||:.|.:..|:|.|||:||.||.|:: |..| :.:...::||:
Mouse   426 KTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDV 489

  Fly   502 Y-IIAALVLYIVFIINKIVWKFVWRKLFGKSNKVSKGKKVK 541
            . .:.|:||.:|||:.|.. .:..||.||...:|.|..|.|
Mouse   490 IGFLLAIVLTVVFIVFKCC-AYGCRKCFGGKGRVKKSHKSK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	156/525 (30%)
		UDPGT	45..530	CDD:278624	157/516 (30%)
Ugt1a6b	NP_958812.3	egt	15..503	CDD:223071	154/522 (30%)
		UDPGT	27..522	CDD:278624	158/530 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840729
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840