Protein Alignment Ugt37D1 and Ugt1a6b

DIOPT Version :10

• Sequence 1: NP_652627.2
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_958812.3
• Gene: Ugt1a6b / 394435
• MGIID: 3580629
• Length: 531
• Species: Mus musculus
• Alignment Length: 561
• Identity: 171/561 - (30%)
• Similarity: 269/561 - (47%)
• Gaps: 75/561 - (13%)

  Fly    20 LLALQTMPQG----TEGANILG---VFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSSVP------ 71
            |.|.||:|.|    ...|::||   :......||::....|::.|:|:||::.|:  ||
Mouse     5 LPAAQTLPAGFLFLVLWASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIVVL--VPEVNLLL 67

  Fly    72 --PKVTHKSINHIVVPMSAED-----------EKVLNDGMAGMVKEKPSIWNTMKSIFSSL-ALL 122
              .|...:.|  ..||.|.|:           :.|....:.|.::|..:...|::..||:. :||
Mouse    68 GESKYYRRKI--FSVPYSLEELQTRFRTFGRNQFVPGAPLMGPLREYRNSMLTLEMFFSNCQSLL 130

  Fly   123 IDKQVDVLEDPRFQELYLNKGNKFDVVFV------GFFFNTYQVALGARFNCPVIISWSGPPMMM 181
            .|...          |...:.||||.:|.      |       |.|....|.|.:..:.|.|..:
Mouse   131 KDSAT----------LSFLRENKFDALFTDPAMPCG-------VILAEYLNLPSVYLFRGFPCSL 178

  Fly   182 VNEVLGNPE-LSSVPQMHISAPPGQPMNFQQRMQNFASTLGFNALNIFLNHKYNKFYDRLWSKDK 245
            .:.:..:|. :|.||:.:...  ...|.|.||:.||...:..|.|...|..||......|..:|.
Mouse   179 EHMLGQSPSPVSYVPRFYTKF--SDHMTFPQRLANFIVNILENYLYYCLYSKYEIIVTDLLKRDV 241

  Fly   246 SMPTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLE-KGKHGA 309
            |:|:..|.    ||.......:.|.| ||.:|.:|.||||..|.| ..|.::.:.::. .|:||.
Mouse   242 SLPSLHQN----SLWLLRYDFVFEYP-RPIMPNMIFIGGINCKKK-GKLTQEFEAYVNASGEHGI 300

  Fly   310 ILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWED--PKNTPGKSANILYKKWLPQDDILA 372
            ::|||||.:  ..|..:....|.:.|..:.|.|:|::..  |.|.   :.|.:..|||||:|:|.
Mouse   301 VVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNL---AKNTILVKWLPQNDLLG 360

  Fly   373 HPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFKAAI 437
            |||.:.||||:|..|:.|...:||||:.:|:|.||..||.::...|.|:.|.:..:..|:.:.|:
Mouse   361 HPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENAL 425

  Fly   438 KEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVH-MNFIASNNLDI 501
            |.||.|..|.:.:...|.|::|||:.|.:..|:|.|||:||.||.|:: |..| :.:...::||:
Mouse   426 KTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDV 489

  Fly   502 Y-IIAALVLYIVFIINKIVWKFVWRKLFGKSNKVSKGKKVK 541
            . .:.|:||.:|||:.|.. .:..||.||...:|.|..|.|
Mouse   490 IGFLLAIVLTVVFIVFKCC-AYGCRKCFGGKGRVKKSHKSK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_652627.2	GT1_Gtf-like	33..471	CDD:340817	137/470 (29%)
Ugt1a6b	NP_958812.3	UDPGT	27..522	CDD:278624	158/530 (30%)