Protein Alignment Ugt37D1 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_652627.2
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_964005.2
• Gene: Ugt1a5 / 394433
• MGIID: 3032634
• Length: 529
• Species: Mus musculus
• Alignment Length: 545
• Identity: 161/545 - (29%)
• Similarity: 270/545 - (49%)
• Gaps: 47/545 - (8%)

  Fly    17 LVALLALQTMPQGTEGANILGVFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSSVPPKVTHK---- 77
            ||.||.|..:| .|||..:| ||.. ..||::....:::.|..:||...|::   |:|..:
Mouse    10 LVGLLLLCALP-WTEGEKVL-VFPV-GGSHWLSMRDVVRELHAQGHQTVVLA---PEVNMRIKEE 68

  Fly    78 ---SINHIVVPMSAEDEKVLNDGM-----AGMVKEKPSIWNTMKSIFSSLALLIDKQVDVLEDPR 134
               :.....||.:.::.:.:.:.:     .|...:|  |:.|.:::.:...:|:....::|.:..
Mouse    69 DFFTFKVYAVPYTRQELEEMMENLKVFFDTGNYMKK--IFKTSEALRNMSTVLLKTCTNILHNES 131

  Fly   135 FQELYLNKGNKFDVVFVGFFFNTYQVALGARF-NCPVIISWSGPPMMMVNEVLGNPELSS-VPQM 197
            ... :|| .:.|||||....|..  .||.|:: ..|.:......|..:..|....|..|| :|.:
Mouse   132 LLH-HLN-SSSFDVVFTDPVFPC--GALLAKYLGIPAVFFLRYIPCGIEYEATQCPSPSSYIPNL 192

  Fly   198 HISAPPGQPMNFQQRMQNFASTLGFNALNIFLNHKYNKFYDRLWSKD-KSMPTFAQAKRNVSLAF 261
            ....  ...|:|.||:||....|....:...|...|......|:.:: .|:..|:.|    |:..
Mouse   193 FTRL--SDHMDFLQRVQNMLYHLVLKYICHLLITPYESLASELFQREVSSVELFSYA----SVWL 251

  Fly   262 CNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLE-KGKHGAILFSLGSNLKGEHIQP 325
            ..|..:.:.| ||.:|.::.||||...:| .||.::.:.::. .|:||.::|||||.:  ..|..
Mouse   252 FRGDFVLDYP-RPIMPNMVFIGGINCVTK-KPLSQEFEAYVNASGEHGIVVFSLGSMV--SEIPE 312

  Fly   326 EVVKTIFKGLSSLKQQVIWKWED--PKNTPGKSANILYKKWLPQDDILAHPKLKLFITHAGKGGV 388
            :....|.:.|..:.|.|:|::..  |.|.   :.|.:..|||||:|:|.|||.:.||||:|..|:
Mouse   313 KKAMEIAEALGRIPQTVLWRYTGTRPSNL---AKNTILVKWLPQNDLLGHPKTRAFITHSGSHGI 374

  Fly   389 AEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFKAAIKEVIENPKYAKTLKSF 453
            .|...:||||:.:|:|.||..||.::...|.|:.|.:..:..|:.:.|:|.||.|..|.:.:...
Mouse   375 YEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRL 439

  Fly   454 SQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVH-MNFIASNNLDIY-IIAALVLYIVFIIN 516
            |.|::|||:.|.:..|:|.|||:||.||.|:: |..| :.:...::||:. .:.|:||.:|||:.
Mouse   440 SSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVF 503

  Fly   517 KIVWKFVWRKLFGKSNKVSKGKKVK 541
            |.. .:..||.||...:|.|..|.|
Mouse   504 KCC-AYGCRKCFGGKGRVKKSHKSK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_652627.2	GT1_Gtf-like	33..471	CDD:340817	124/455 (27%)
Ugt1a5	NP_964005.2	UDPGT	26..520	CDD:278624	148/519 (29%)