DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37D1 and Ugt301D1

DIOPT Version :9

Sequence 1:	NP_001285989.1	Gene:	Ugt37D1 / 53511	FlyBaseID:	FBgn0040260	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	568	Identity:	178/568 - (31%)
Similarity:	280/568 - (49%)	Gaps:	85/568 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 WIGCSLGGLLVALLALQTMPQGTEGANILGVFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSSVPP 72
            |:...|.|||          :...|:.||.:....:|||::........|..:||:||.|::.|.
  Fly    10 WMLIFLIGLL----------EFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPT 64

  Fly    73 KVTHKSINHIVVPMSAEDEKVLNDGMAGMVKEKPSIWN-TMKSIFSSLAL-----LIDKQVDVLE 131
            |..|:::..|::..|.:..|..         .|.:|:: ...|.|::|.|     |:..: ...:
  Fly    65 KHPHENLTEIIISPSFDIPKHF---------PKENIFSMQFVSDFNNLELWWTIGLMTTE-HAFK 119

  Fly   132 DPRFQELYLNKGNKFDVVFVGFFFNTYQVALGARFNCPVIISWSGPPMMMVNEVLG--NPELSSV 194
            ||:.::|..:|.:.:|:|.:..||:...:..|.||||||:...:......::..:|  .| .|.:
  Fly   120 DPKVKKLIESKDDHYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTP-WSLI 183

  Fly   195 PQMHISAPPGQPMNFQQRMQNFASTLGFNALNIFLNHKYNKFYD---RLW--------------- 241
            |.:.:|        ...||     |.|..|.|.:|:     .||   |.|
  Fly   184 PHLLLS--------HTDRM-----TFGQRAYNAYLS-----LYDAVMRRWVYLPKMQKLAEKYFQ 230

  Fly   242 -SKDKSMPTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLEKG 305
             |.:..:|.....:||:||...|.|...:.| ||::||:|::||..:: ||..||.|:|.||:..
  Fly   231 GSIEGPLPNVLDLERNISLVLINAHRSIDLP-RPSMPGLIDVGGAHIQ-KPKQLPTDLQNFLDNA 293

  Fly   306 KHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWEDPK--NTPGKSANILYKKWLPQD 368
            .:|.|.||:||.:|...:..|....|.|....||||||||:|:..  :.|   :|::.|||:||:
  Fly   294 TYGVIYFSMGSYVKSTDLPQEKTALILKAFGQLKQQVIWKFENDSIGDLP---SNVMIKKWMPQN 355

  Fly   369 DILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEF 433
            ||||||.:||||||.|..|..|..|.|||||.:|::.||..|..|.|..||...|..:.|..|:.
  Fly   356 DILAHPNVKLFITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDL 420

  Fly   434 KAAIKEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVHMNFIASNN 498
            ...|:.:|.:|:|.::....||.:||.|:.|.:...:|.||:|||.||.|::|   |..||..:.
  Fly   421 VRNIETLINDPQYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGARHLKS---HGAFIPLHQ 482

  Fly   499 LDIYIIAALVLYIVFIINKIVWKFV------WRKLFGK-SNKVSKGKK 539
            ..:..:...:|...|:...:.|:.:      |.|  |: |||:::|||
  Fly   483 YLLLDVLGCLLLGAFLAIWLPWRMIRRVHKWWLK--GESSNKLNEGKK 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	162/515 (31%)
Ugt37D1	NP_001285989.1	UDPGT	45..530	CDD:278624	162/519 (31%)
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	165/517 (32%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	157/482 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	6	6.010