Protein Alignment Ugt37D1 and Ugt2b10

DIOPT Version :10

• Sequence 1: NP_652627.2
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001178605.1
• Gene: Ugt2b10 / 305264
• RGDID: 1309989
• Length: 532
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 148/554 - (26%)
• Similarity: 252/554 - (45%)
• Gaps: 56/554 - (10%)

  Fly    16 LLVALLALQTMPQGTEGANILGVFTSHSPSHFIVHMSIMKTLAEKGHNVTVV---SSVPPKVTHK 77
            ||:.||.|........|..:| |:.... ||::....|:..|.:|||.|||:   :|:..:|.:.
  Rat     9 LLLLLLQLSDFFGSGTGGKVL-VWPMEF-SHWLNLRVILDELLKKGHEVTVLRPSASLSYEVDNT 71

  Fly    78 S-INHIVVPMS---AEDEKVLNDGMAGMVKEKP--SIWNTM----------KSIFSSLALLIDKQ 126
            | |.....|.|   .|.::...:.:...:.|.|  |.|...          ...|.||.
  Rat    72 SAIEFETYPTSYSLTEVDEFFWESLRKYIYELPKQSFWGYFLMFQELVWVDSDYFESLC------ 130

  Fly   127 VDVLEDPRFQELYLNKGNKFDVVFVGFFFNTYQVALGARFNCPVIISWSGPPMMMVNEVLGN--- 188
            .||:.:........|.|  |||:....|.....: |......|::.|....|.....:..|.
  Rat   131 KDVVFNKELMTKLQNSG--FDVILADPFIPCGDL-LAEILKIPLVYSLRFFPGSTYEKYSGGLPM 192

  Fly   189 -PELSSVPQMHISAPPGQPMNFQQRMQNFASTLGFNA-LNIFLNHKYNKFYDRLWSKDKSMPTFA 251
             |....:....:|    ..|.|.:||::....|.|:. ...|...|:|:.|..:..:.   .|.:
  Rat   193 PPSYVPIAMSELS----DRMTFVERMKHMIYVLCFDFWFQAFNEKKWNELYTEVLGRP---TTLS 250

  Fly   252 QAKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLE-KGKHGAILFSLG 315
            :......:.....:...|.| .|.:|....:||:..: ...|||::|::|:: .|:||.::||||
  Rat   251 ETMAKADIWLIRTYWDLEFP-HPVLPNFDFVGGLHCR-PAKPLPKEIEDFVQSSGEHGVVVFSLG 313

  Fly   316 SNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWEDPKNTPGKSANILYKKWLPQDDILAHPKLKLFI 380
            |.:  .::..|....|..||:.:.|:|:|::|..|.....|...|| ||:||:|:|.|||.:.||
  Rat   314 SMV--GNLTEERANVIAAGLAQIPQKVLWRFEGKKPETLGSNTRLY-KWIPQNDLLGHPKTRAFI 375

  Fly   381 THAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFKAAIKEVIENPK 445
            ||.|..|:.||.|||:|::.:|:|.||..|...|...|..::|...|:...:...|:|.:..:|.
  Rat   376 THGGTNGIYEAIYHGIPVVGIPLFGDQYDNIVHLKTKGAAVRLDFLTMSSTDLFTALKTITNDPS 440

  Fly   446 YAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVHMNFIASNNLDIY-IIAALVL 509
            |.:.....|:::.|:|:.|.:..|:|.|:|:||.||.|::.....::::..::||:. .:.|.|:
  Rat   441 YKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWVQYHSLDVIGFLLACVV 505

  Fly   510 YIVFIINKIVWKFVWRKLFGKSNKVSKGKKVKKQ 543
            .::||:.|..       ||........|:|.|::
  Rat   506 TVMFILKKCC-------LFCCQKFTKAGRKKKRE 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_652627.2	GT1_Gtf-like	33..471	CDD:340817	122/462 (26%)
Ugt2b10	NP_001178605.1	UDPGT	26..529	CDD:278624	140/532 (26%)