Protein Alignment Ugt37D1 and Ugt2b1

DIOPT Version :10

• Sequence 1: NP_652627.2
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_775417.1
• Gene: Ugt2b1 / 286954
• RGDID: 708541
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 527
• Identity: 159/527 - (30%)
• Similarity: 264/527 - (50%)
• Gaps: 60/527 - (11%)

  Fly    45 SHFIVHMSIMKTLAEKGHNVTV-VSSV-----PPKVTHKSINHIV--VPMSAEDEKVLNDGMAGM 101
            ||:|....|:..||::||.||| |||.     |.|  ..|||..:  ||:|..|   |....|..
  Rat    34 SHWINIKIILNELAQRGHEVTVLVSSASILIEPTK--ESSINFEIYSVPLSKSD---LEYSFAKW 93

  Fly   102 VK------EKPSIWNTMKSIFSSLALLIDKQVDVLEDPRFQELYLNK-------GNKFDVVFVGF 153
            :.      |..|||    :.:|.:..:.::..||:|: ..:.|..||       |::|||:....
  Rat    94 IDEWTRDFETLSIW----TYYSKMQKVFNEYSDVVEN-LCKALIWNKSLMKKLQGSQFDVILADA 153

  Fly   154 FFNTYQVALGARFNCPVIISWSGPPMMMVNEVLGNPEL--SSVPQMHISAPPGQPMNFQQRMQNF 216
            .....:: |......|::.|....|.....:..|...|  |.||.  :.:.....|.|.:|::|.
  Rat   154 VGPCGEL-LAELLKTPLVYSLRFCPGYRCEKFSGGLPLPPSYVPV--VLSELSDRMTFVERVKNM 215

  Fly   217 ASTLGFNA-LNIFLNHKYNKFYDRLWSKDKSMPTFAQAKRNVSL--AFCNGHGISEGPIRPNVPG 278
            ...|.|:. ...|....:::||..:..:..:: |....|.::.|  .|.:    .|.| .|.:|.
  Rat   216 LQMLYFDFWFQPFKEKSWSQFYSDVLGRPTTL-TEMMGKADIWLIRTFWD----LEFP-HPFLPN 274

  Fly   279 VIEIGGIQVKSKPDPLPEDIQEFLE-KGKHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQQV 342
            ...:||:..| ...|||.:::||:: .|:||.::|||||.:|  ::..|....:...|:.:.|:|
  Rat   275 FDFVGGLHCK-PAKPLPREMEEFVQSSGEHGVVVFSLGSMVK--NLTEEKANVVASALAQIPQKV 336

  Fly   343 IWKWEDPK-NTPGKSANILYKKWLPQDDILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVFAD 406
            :|:::..| :|.|.:.. || ||:||:|:|.|||.|.|:.|.|..|:.||.|||:|::.:|:|||
  Rat   337 VWRFDGKKPDTLGSNTR-LY-KWIPQNDLLGHPKTKAFVAHGGTNGIYEAIYHGIPIVGIPLFAD 399

  Fly   407 QPGNADKLVASGYGLQLPLATLDVDEFKAAIKEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYW 471
            ||.|.:.:||.|..:::..:.|.......|:|.|:.:|.|.:.....|:::.|:|:.|.:..|:|
  Rat   400 QPDNINHMVAKGAAVRVDFSILSTTGLLTALKIVMNDPSYKENAMRLSRIHHDQPVKPLDRAVFW 464

  Fly   472 TEYVIRHHGAAHMQSPLVHMNFIASNNLDIY-IIAALVLYIVFIINKIVWKFVWRKLFGKSNKVS 535
            .|||:||.||.|::|.|..:::...::||:. .:...|:.:||||.|..       ||......:
  Rat   465 IEYVMRHKGAKHLRSTLHDLSWFQYHSLDVIGFLLLCVVGVVFIITKFC-------LFCCRKTAN 522

  Fly   536 KGKKVKK 542
            .|||.|:
  Rat   523 MGKKKKE 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_652627.2	GT1_Gtf-like	33..471	CDD:340817	134/453 (30%)
Ugt2b1	NP_775417.1	UDPGT	24..527	CDD:278624	157/523 (30%)