Protein Alignment Ugt37D1 and Ugt2b15

DIOPT Version :10

• Sequence 1: NP_652627.2
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_695226.3
• Gene: Ugt2b15 / 266685
• RGDID: 628623
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 549
• Identity: 158/549 - (28%)
• Similarity: 254/549 - (46%)
• Gaps: 102/549 - (18%)

  Fly    45 SHFIVHMSIMKTLAEKGHNVTVVSSVPPKVTHKSINHIVVPMSAEDEK-------VLNDGMAGMV 102
            ||::...:|:..|.::||.|||:.        .|..:::.|..:.|.|       |..|.:....
  Rat    34 SHWMNIKTILDELVQRGHEVTVLK--------PSAYYVLDPKKSPDLKFETFPTSVSKDELENYF 90

  Fly   103 KEKPSIW--NTMKSIFSSLALLIDKQVDVLEDPRFQELYLN---------------KGNKFDVVF 150
            .:...:|  ...:....|.:.|:...:|     .|.:.||:               :.:||||:
  Rat    91 IKLVDVWTYELQRDTCLSYSPLLQNMID-----GFSDYYLSLCKDTVSNKQLMAKLQESKFDVL- 149

  Fly   151 VGFFFNTYQVALGARFNCPVIISWSGPPMMMVNEVLGNPELSSV---PQMHIS-------APP-- 203
                           .:.||.....     ::.|||..|.|.|:   |...|.       .||
  Rat   150 ---------------LSDPVAACGE-----LIAEVLHIPFLYSLRFSPGYKIEKSSGRFILPPSY 194

  Fly   204 --------GQPMNFQQRMQNFASTLGFNALNIFLNHKYN-KFYDRLWSKDKSMP-TFAQAKRNVS 258
                    |.||.|..|::|...||.|:    |..|.:| |.:|..:|:....| |.|:......
  Rat   195 VPVILSGMGGPMTFIDRVKNMICTLYFD----FWFHMFNAKKWDPFYSEILGRPTTLAETMGKAE 255

  Fly   259 LAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLE-KGKHGAILFSLGSNLKGEH 322
            :.....:...|.| .|.:|.|..|||:|.: .|.|||:|:::|:: .|:||.::|||||.:..
  Rat   256 MWLIRSYWDLEFP-HPTLPNVDYIGGLQCR-PPKPLPKDMEDFVQSSGEHGVVVFSLGSMVSS-- 316

  Fly   323 IQPEVVKTIFKGLSSLKQQVIWKWEDPKNTPGKSANILYKKWLPQDDILAHPKLKLFITHAGKGG 387
            :..|....|...|:.:.|:|:||: |.|.......|....|||||:|:|.|||.|.|:||.|..|
  Rat   317 MTEEKANAIAWALAQIPQKVLWKF-DGKTPATLGPNTRVYKWLPQNDLLGHPKTKAFVTHGGANG 380

  Fly   388 VAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFKAAIKEVIENPKYAKTLKS 452
            |.||.|||:||:.:|:|.:|..|...:||.|..:.|.:.|:...:...|:||:|.||.|.|....
  Rat   381 VYEAIYHGIPMVGIPMFGEQHDNIAHMVAKGAAVTLNIRTMSKSDLFNALKEIINNPFYKKNAVW 445

  Fly   453 FSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVH-MNFIASNNLDI--YIIAALVLYIVFI 514
            .|.::.|:|:.|.:..|:|.|:|:||.||.|:: ||.| :.:...::||:  :::....:..|..
  Rat   446 LSTIHHDQPMKPLDKAVFWIEFVMRHKGAKHLR-PLGHNLPWYQYHSLDVIGFLLTCSAVIAVLT 509

  Fly   515 INKIVWKFVWRKLFGKSNKVSKGKKVKKQ 543
            :...:  |::| ||     |.|.||:|.:
  Rat   510 VKSFL--FIYR-LF-----VKKEKKMKNE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_652627.2	GT1_Gtf-like	33..471	CDD:340817	135/472 (29%)
Ugt2b15	NP_695226.3	UDPGT	24..527	CDD:278624	156/544 (29%)